Diosmin
Diosmin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bruselix bruising | unapproved drug other | 2024-10-11 |
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Clinical
Clinical Trials
76 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | — | 1 | 1 | 2 | 6 | 10 |
| Venous insufficiency | D014689 | — | — | — | — | 4 | 4 | 1 | 9 |
| Hemorrhoids | D006484 | EFO_0009552 | K64 | — | — | 1 | 1 | 3 | 5 |
| Thrombosis | D013927 | — | — | — | — | — | 1 | — | 1 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | — | — | 1 | — | 1 |
| Postphlebitic syndrome | D011186 | — | I87.0 | — | — | — | 1 | — | 1 |
| Postthrombotic syndrome | D054070 | EFO_0007452 | I87.0 | — | — | — | 1 | — | 1 |
| Lymphedema | D008209 | HP_0001004 | — | — | — | — | 1 | — | 1 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | 1 | — | 1 |
| Rectal fistula | D012003 | HP_0010447 | K60.3 | — | — | — | 1 | — | 1 |
Show 1 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | — | 1 | — | 3 | 4 |
| Fatty liver | D005234 | EFO_0003934 | — | — | — | 1 | — | 3 | 4 |
| Alcoholic fatty liver | D005235 | — | K70.0 | — | — | 1 | — | 3 | 4 |
| Ulcer | D014456 | MPATH_579 | — | — | — | 2 | — | 2 | 4 |
| Osteoporosis | D010024 | HP_0000939 | M81.0 | — | 1 | 1 | — | 1 | 3 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | — | 1 | — | 1 | 2 |
| Infertility | D007246 | HP_0000789 | — | — | 1 | 1 | — | 1 | 2 |
| Ovarian hyperstimulation syndrome | D016471 | — | — | — | 1 | 1 | — | 1 | 2 |
| Metabolic bone diseases | D001851 | HP_0000938 | — | — | 1 | 1 | — | — | 2 |
| Heart disease risk factors | D000082742 | — | — | — | — | 1 | — | — | 1 |
Show 7 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | 2 | — | — | 4 | 6 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 2 | — | — | — | 2 |
| Myalgia | D063806 | HP_0003326 | M79.1 | 1 | 1 | — | — | — | 2 |
| Insulin resistance | D007333 | HP_0000855 | — | — | 1 | — | — | — | 1 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | 1 | 1 | — | — | — | 1 |
| Covid-19 | D000086382 | — | — | — | 1 | — | — | — | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | 1 | — | — | — | 1 |
| Vomiting | D014839 | HP_0002013 | R11.1 | — | 1 | — | — | — | 1 |
| Nausea | D009325 | HP_0002018 | R11.0 | — | 1 | — | — | — | 1 |
| Headache | D006261 | HP_0002315 | R51 | — | 1 | — | — | — | 1 |
Show 14 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
| Skin neoplasms | D012878 | EFO_0004198 | C44 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | — | — | — | — | 3 | 3 |
| Liver diseases | D008107 | HP_0002910 | K70-K77 | — | — | — | — | 3 | 3 |
| Body weight | D001835 | EFO_0004338 | — | — | — | — | — | 3 | 3 |
| Body weight changes | D001836 | — | — | — | — | — | — | 2 | 2 |
| Skin ulcer | D012883 | HP_0200042 | L98.4 | — | — | — | — | 2 | 2 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 2 | 2 |
| Varicose veins | D014648 | HP_0002619 | I83.90 | — | — | — | — | 2 | 2 |
| Exercise tolerance | D017079 | — | — | — | — | — | — | 2 | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Vascular ring | D000073872 | — | Q25.45 | — | — | — | — | 1 | 1 |
Show 35 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Diosmin |
| INN | diosmin |
| Description | Diosmin is a disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and an anti-inflammatory agent. It is a glycosyloxyflavone, a rutinoside, a disaccharide derivative, a monomethoxyflavone and a dihydroxyflavanone. It is functionally related to a diosmetin. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc(-c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2)cc1O |
Identifiers
| PDB | — |
| CAS-ID | 520-27-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL231884 |
| ChEBI ID | 4631 |
| PubChem CID | 5281613 |
| DrugBank | DB08995 |
| UNII ID | 7QM776WJ5N (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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610 adverse events reported
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