Diosmin
Diosmin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
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Labels
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| bruselix bruising | unapproved drug other | 2024-10-11 |
Indications
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Clinical
Clinical Trials
75 clinical trials
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Indications Phases 4
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 2 | 2 |
| Skin ulcer | D012883 | HP_0200042 | L98.4 | — | — | — | — | 2 | 2 |
| Lipedema | D065134 | — | — | — | — | — | — | 1 | 1 |
| Systemic scleroderma | D012595 | EFO_0000717 | M34.0 | — | — | — | — | 1 | 1 |
| Diffuse scleroderma | D045743 | EFO_0000404 | — | — | — | — | — | 1 | 1 |
| Sclerosis | D012598 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Diosmin |
| INN | diosmin |
| Description | Diosmin is a disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and an anti-inflammatory agent. It is a glycosyloxyflavone, a rutinoside, a disaccharide derivative, a monomethoxyflavone and a dihydroxyflavanone. It is functionally related to a diosmetin. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc(-c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2)cc1O |
Identifiers
| PDB | — |
| CAS-ID | 520-27-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL231884 |
| ChEBI ID | 4631 |
| PubChem CID | 5281613 |
| DrugBank | DB08995 |
| UNII ID | 7QM776WJ5N (ChemIDplus, GSRS) |
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Trends
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Safety
Black-box Warning
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Adverse Events
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600 adverse events reported
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