Dimethicone
Dimethicone is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Commercial
Therapeutic Areas
Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 2-oak mix, red/white pollen 3-oak mix, black/blackjack/post pollen 3-ragweed mix, giant/short/western pollen 4-pine mix, austrian/loblolly/scotch/w... | Biologic Licensing Application | 2011-03-11 |
| 3ce matte lip crayon dubious | unapproved drug other | 2016-10-11 |
| 3ce skin tone control primer ice vanilla | OTC monograph final | 2016-10-14 |
| 3ce skin tone control primer mild peach | OTC monograph final | 2016-10-14 |
| 3ce skin tone control primer pure violet | OTC monograph final | 2016-10-14 |
| 3ce white milk crea m | OTC monograph final | 2016-10-14 |
| 3m cavilon durable barrier | Export only | 2024-08-01 |
| a and a diaper rash cream | OTC monograph final | 2013-07-14 |
| a and d | C200263 | 2024-12-06 |
| a mold mixture absidia ramosa acrothecium robustum alternaria alternata aspergillus flavus aspergillus fumigatus aspergillus mixture aspergillus ni... | Biologic Licensing Application | 2009-11-17 |
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Indications
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Agency Specific
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Clinical
Clinical Trials
129 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 2 | 2 | 1 | 4 | 7 |
| Lice infestations | D010373 | — | B85.2 | — | 1 | — | 1 | 4 | 6 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | 1 | — | — | 3 | 1 | 5 |
| Healthy volunteers/patients | — | — | — | 2 | — | — | 1 | 2 | 5 |
| Dermatitis | D003872 | — | L30.9 | 1 | 1 | — | 1 | 3 | 5 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | 1 | 2 | 3 |
| Colonoscopy | D003113 | — | — | — | — | — | 3 | — | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 2 | 3 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | 1 | 2 | 3 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | 1 | 1 | 2 |
Show 18 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Abdominal pain | D015746 | EFO_0003766 | R10.9 | 2 | 1 | 1 | — | — | 4 |
| Colorectal neoplasms | D015179 | — | — | — | — | 1 | — | 3 | 4 |
| Stomach diseases | D013272 | — | — | — | 2 | 1 | — | 1 | 3 |
| Capsule endoscopy | D053704 | — | — | — | 1 | 1 | — | 2 | 3 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | 1 | — | 2 | 3 |
| Hydrocephalus | D006849 | — | G91 | — | 1 | 2 | — | — | 3 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | 1 | — | 1 | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 1 | 1 | — | 1 | 2 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | 1 | — | 1 | — | — | 2 |
| Vomiting | D014839 | — | R11.1 | — | — | 1 | — | 1 | 2 |
Show 11 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pediculus | D010374 | — | — | — | 1 | — | — | 2 | 3 |
| Gastroschisis | D020139 | EFO_1000949 | Q79.3 | 1 | 1 | — | — | — | 2 |
| Radiodermatitis | D011855 | — | L58 | 1 | 1 | — | — | 1 | 2 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 1 | — | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | 1 | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | — | 1 | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | — | 1 | — | — | — | 1 |
| Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
| Astrocytoma | D001254 | EFO_0000271 | — | — | 1 | — | — | — | 1 |
| Herpes simplex | D006561 | — | B00 | — | 1 | — | — | — | 1 |
Show 12 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Actinic keratosis | D055623 | — | L57.0 | 1 | — | — | — | — | 1 |
| Keratosis | D007642 | — | — | 1 | — | — | — | — | 1 |
| Hemorrhage | D006470 | MP_0001914 | R58 | 1 | — | — | — | — | 1 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pressure ulcer | D003668 | — | L89 | — | — | — | — | 3 | 3 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 3 | 3 |
| Urinary incontinence | D014549 | — | R32 | — | — | — | — | 2 | 2 |
| Stress urinary incontinence | D014550 | — | — | — | — | — | — | 2 | 2 |
| Enuresis | D004775 | — | R32 | — | — | — | — | 2 | 2 |
| Contraception | D003267 | — | — | — | — | — | — | 2 | 2 |
| Parasitic diseases | D010272 | EFO_0001067 | B88 | — | — | — | — | 2 | 2 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 2 | 2 |
| Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 2 | 2 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | — | — | — | — | 2 | 2 |
Show 43 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Dimethicone |
| INN | dimeticone |
| Description | Polydimethylsiloxane (PDMS), also known as dimethylpolysiloxane or dimethicone, is a silicone polymer with a wide variety of uses, from cosmetics to industrial lubrication.
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108200 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 92RU3N3Y1O (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Additional graphs summarizing 59,820 documents
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Safety
Black-box Warning
Black-box warning for: 2-oak mix, red/white pollen 3-oak mix, black/blackjack/post pollen 3-ragweed mix, giant/short/western pollen 4-pine mix, austrian/loblolly/scotch/w..., A mold mixture absidia ramosa acrothecium robustum alternaria alternata aspergillus flavus aspergillus fumigatus aspergillus mixture aspergillus ni..., Pollens - trees, sycamore, american (eastern) platanus occidentallis animal allergens, ap cattle hair and dander animal allergens, ap dog hair and ..., Pollens - trees, sycamore, american (eastern) platanus occidentallis animal allergens, ap cattle hair and dander animal allergens, ap horse hair an...
Adverse Events
Top Adverse Reactions
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39,073 adverse events reported
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