Diethylcarbamazine
Hetrazan (diethylcarbamazine) is a small molecule pharmaceutical. Diethylcarbamazine was first approved as Hetrazan on 1982-01-01. It is used to treat filarial elephantiasis, loiasis, and pulmonary eosinophilia in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Diethylcarbamazine citrate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| HETRAZAN | Lederle Laboratories | N-006459 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| filarial elephantiasis | EFO_0007272 | D004605 | B74.0 |
| loiasis | — | D008118 | B74.3 |
| pulmonary eosinophilia | EFO_0007257 | D011657 | J82.81 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
24 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 1 | 1 | — | 1 | 4 | 7 |
| Loiasis | D008118 | — | B74.3 | — | 2 | — | 1 | 1 | 4 |
| Parasitic diseases | D010272 | EFO_0001067 | B88 | — | — | — | 1 | 1 | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Filariasis | D005368 | — | B74 | 1 | 4 | 2 | — | 9 | 16 |
| Filarial elephantiasis | D004605 | EFO_0007272 | B74.0 | 1 | 4 | 2 | — | 7 | 14 |
| Elephantiasis | D004604 | EFO_0004711 | — | 1 | 4 | 2 | — | 7 | 14 |
| Yaws | D015001 | EFO_0007548 | A66 | — | 1 | 1 | — | — | 2 |
| Scabies | D012532 | — | B86 | — | — | 1 | — | 1 | 2 |
| Trachoma | D014141 | — | A71 | — | — | 1 | — | — | 1 |
| Strongyloidiasis | D013322 | EFO_0007501 | B78 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Onchocerciasis | D009855 | EFO_0007402 | B73 | — | 2 | — | — | 3 | 5 |
| Wuchereria bancrofti | D014958 | — | — | 1 | 1 | — | — | — | 2 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | — | — | 1 |
| Eosinophilia | D004802 | HP_0001880 | D72.1 | — | 1 | — | — | — | 1 |
| Ocular onchocerciasis | D015827 | EFO_0007398 | B73 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Communicable diseases | D003141 | — | — | — | — | — | — | 2 | 2 |
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | — | — | — | — | 2 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 2 | 2 |
| Impetigo | D007169 | EFO_1000714 | L01 | — | — | — | — | 1 | 1 |
| Mansonelliasis | D008368 | EFO_0007357 | B74.4 | — | — | — | — | 1 | 1 |
| Disease | D004194 | EFO_0000408 | R69 | — | — | — | — | 1 | 1 |
| Neglected diseases | D058069 | — | — | — | — | — | — | 1 | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Diethylcarbamazine |
| INN | diethylcarbamazine |
| Description | Diethylcarbamazine is a N-methylpiperazine and a N-carbamoylpiperazine. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCN(CC)C(=O)N1CCN(C)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 90-89-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL684 |
| ChEBI ID | 4527 |
| PubChem CID | 3052 |
| DrugBank | DB00711 |
| UNII ID | V867Q8X3ZD (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 3,319 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,565 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use