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Drug ReportsDienestrol
Dienestrol
Dv, Estraguard (dienestrol) is a small molecule pharmaceutical. Dienestrol was first approved as Dienestrol on 1982-01-01. It is used to treat atrophic vaginitis and vulvar lichen sclerosus in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
Trade Name
FDA
EMA
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dienestrol
Tradename
Company
Number
Date
Products
DIENESTROLJohnson & JohnsonN-006110 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
vulvar lichen sclerosus—D007724N90.4
atrophic vaginitisEFO_1001271D059268—
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03C: Estrogens, sex hormones and modulators of the genital system
— G03CB: Synthetic estrogens, plain
— G03CB01: Dienestrol
— G03CC: Estrogens, combinations with other drugs
— G03CC02: Dienestrol
HCPCS
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Clinical
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Drug
General
Drug common nameDienestrol
INNdienestrol
Description
Dienestrol is an olefinic compound that is hexa-2,4-diene substituted by 4-hydroxyphenyl groups at positions 3 and 4 respectively. It has a role as a xenoestrogen. It is a member of phenols and an olefinic compound.
Classification
Small molecule
Drug classestrogens
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Structure (InChI/SMILES or Protein Sequence)
C/C=C(C(=C/C)/c1ccc(O)cc1)\c1ccc(O)cc1
Identifiers
PDB—
CAS-ID84-17-3
RxCUI—
ChEMBL IDCHEMBL1018
ChEBI ID—
PubChem CID667476
DrugBankDB00890
UNII IDRRW32X4U1F (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
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Estimated US medical usage
Dienestrol
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
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Additional graphs summarizing 1,199 documents
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Safety
Black-box Warning
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128 adverse events reported
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