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Drug ReportsDicloxacillin
Dicloxacillin
Dicloxacillin (dicloxacillin) is a small molecule pharmaceutical. Dicloxacillin was first approved as Dynapen on 1982-01-01. It is used to treat bacterial infections, bacterial pneumonia, cellulitis, osteomyelitis, and postoperative complications amongst others in the USA.
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Variants
Financial
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Safety
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FDA approval date
EMA approval date
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Study first post date
Last update post date
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Primary completion date
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Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dicloxacillin sodium
Tradename
Company
Number
Date
Products
DYNAPENBristol Myers SquibbN-050337 DISCN1982-01-01
1 products
PATHOCILWyethN-050011 DISCN1982-01-01
2 products, RLD
PATHOCILWyethN-050092 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
dicloxacillin sodiumANDA2024-01-18
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01C: Beta-lactam antibacterials, penicillins
J01CF: Beta-lactamase resistant penicillins
J01CF01: Dicloxacillin
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteomyelitisD010019EFO_0003102M86112
BacteremiaD016470EFO_0003033R78.81112
EndocarditisD004696HP_010058422
Infectious arthritisD001170EFO_1001351M0011
Atopic dermatitisD003876EFO_0000274L2011
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial infectionsD001424A4911
Gram-positive bacterial infectionsD01690811
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Drug interactionsD00434711
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
RuptureD01242122
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDicloxacillin
INNdicloxacillin
Description
Dicloxacillin is a penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. It has a role as an antibacterial drug. It is a penicillin and a dichlorobenzene. It is a conjugate acid of a dicloxacillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB
CAS-ID3116-76-5
RxCUI
ChEMBL IDCHEMBL893
ChEBI ID4511
PubChem CID18381
DrugBankDB00485
UNII IDCOF19H7WBK (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Dicloxacillin
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,818 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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307 adverse events reported
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