Dexpanthenol
Berocca Pn, Infuvite, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc (dexpanthenol) is a small molecule pharmaceutical. Dexpanthenol was first approved as M.v.i.-12 lyophilized on 1985-08-08.
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Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Combinations
Infuvite (discontinued: Berocca pn, M.v.c. 9+, M.v.i., M.v.i. lyophilized, Mvc)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Alpha-tocopherol acetate
+
Ascorbic acid
+
Biotin
+
Cholecalciferol
+
Cyanocobalamin
+
Dexpanthenol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
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Riboflavin 5'-phosphate sodium
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Thiamine hydrochloride
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Vitamin a palmitate
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cholecalciferol
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Cyanocobalamin
+
Dexpanthenol
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Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Tocopherol acetate
+
Vitamin a
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 24 alopecia reliefshampoo | unapproved drug other | 2020-08-08 |
| 574h cell care | unapproved drug other | 2020-06-19 |
| aape hair ampoule | unapproved drug other | 2021-05-28 |
| adult infuvite multiple vitamins | New Drug Application | 2019-05-14 |
| adult infuvite multiple vitamins for infusion pharmacy bulk | New Drug Application | 2013-01-01 |
| aewajin hasuoshampoo | unapproved drug other | 2022-01-02 |
| anubis barcelona regul oil | OTC monograph final | 2023-09-01 |
| ato standard intensivecream | unapproved drug other | 2021-11-23 |
| b-plex 100 | unapproved drug other | 2020-12-04 |
| babysons | OTC monograph not final | 2020-01-23 |
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A11: Vitamins
— A11H: Other plain vitamin preparations in atc
— A11HA: Other plain vitamin preparations in atc
— A11HA30: Dexpanthenol
D: Dermatologicals
— D03: Preparations for treatment of wounds and ulcers
— D03A: Cicatrizants
— D03AX: Other cicatrizants in atc
— D03AX03: Dexpanthenol
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01X: Other ophthalmologicals in atc
— S01XA: Other ophthalmologicals in atc
— S01XA12: Dexpanthenol
HCPCS
No data
Clinical
Clinical Trials
48 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Erythema | D004890 | HP_0010783 | L53.9 | — | 1 | — | 1 | 1 | 3 |
| Wound healing | D014945 | GO_0042060 | — | — | — | — | 2 | — | 2 |
| Patient compliance | D010349 | — | — | — | — | — | 1 | — | 1 |
| Acne vulgaris | D000152 | EFO_0003894 | L70 | — | — | — | 1 | — | 1 |
| Gene expression | D015870 | — | — | — | — | — | 1 | — | 1 |
| Cell proliferation | D049109 | GO_0008283 | — | — | — | — | 1 | — | 1 |
| Pruritus | D011537 | HP_0000989 | L29 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 1 | — | 1 | 2 |
| Diabetic foot | D017719 | EFO_1001459 | — | — | — | 2 | — | — | 2 |
| Leukemia | D007938 | — | C95 | — | — | 1 | — | — | 1 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | — | 1 | — | — | 1 |
| Cold temperature | D003080 | — | — | — | — | 1 | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | — | 1 | — | — | 1 |
| Exanthema | D005076 | HP_0000988 | — | — | — | 1 | — | — | 1 |
| Radiodermatitis | D011855 | — | L58 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomatitis | D013280 | EFO_1001904 | K12.1 | — | 1 | — | — | 1 | 2 |
| Skin abnormalities | D012868 | HP_0000951 | Q82.9 | — | 1 | — | — | 1 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | — | 1 |
| Human influenza | D007251 | EFO_0007328 | J11.1 | — | 1 | — | — | — | 1 |
| Traumatic brain injuries | D000070642 | — | S06 | — | 1 | — | — | — | 1 |
| Hemorrhagic shock | D012771 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dry eye syndromes | D015352 | — | H04.12 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Burns | D002056 | — | T30.0 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Head and neck neoplasms | D006258 | — | — | — | — | — | — | 2 | 2 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | — | — | 1 | 1 |
| Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | — | — | — | 1 | 1 |
| Xerostomia | D014987 | — | K11.7 | — | — | — | — | 1 | 1 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 1 | 1 |
| Gingivitis | D005891 | HP_0000230 | K05.10 | — | — | — | — | 1 | 1 |
| Corneal diseases | D003316 | — | H18.9 | — | — | — | — | 1 | 1 |
| Vomiting | D014839 | HP_0002013 | R11.1 | — | — | — | — | 1 | 1 |
| Mitral valve insufficiency | D008944 | HP_0001653 | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Dexpanthenol |
| INN | dexpanthenol |
| Description | Panthenol (also called pantothenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms, it is quickly oxidized to pantothenic acid. It is a viscous transparent liquid at room temperature. Panthenol is used in pharmaceutical and cosmetic products as a moisturizer and to improve wound healing.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(CO)[C@@H](O)C(=O)NCCCO |
Identifiers
| PDB | — |
| CAS-ID | 81-13-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200979 |
| ChEBI ID | 27373 |
| PubChem CID | 4678 |
| DrugBank | — |
| UNII ID | 1O6C93RI7Z (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,419 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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871 adverse events reported
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