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Drug ReportsDexketoprofen
Dexketoprofen
Dexketoprofen is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
musculoskeletal diseasesD009140
stomatognathic diseasesD009057
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
keralytunapproved drug other2024-03-27
ketopheneunapproved drug other2016-07-21
ketoprofenANDA2025-05-26
kiprofenANDA2025-01-30
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M01: Antiinflammatory and antirheumatic products
— M01A: Antiinflammatory and antirheumatic products, non-steroids
— M01AE: Propionic acid derivatives, antiinflammatory and antirheumatic products
— M01AE17: Dexketoprofen
— M02: Topical products for joint and muscular pain
— M02A: Topical products for joint and muscular pain
— M02AA: Antiinflammatory preparations, non-steroids for topical use
— M02AA27: Dexketoprofen
N: Nervous system drugs
— N02: Analgesics
— N02A: Opioid analgesics
— N02AJ: Opioids in combination with non-opioid analgesics
— N02AJ14: Tramadol and dexketoprofen
HCPCS
No data
Clinical
Clinical Trials
109 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative painD010149—G89.18—217919
Acute painD059787—R521123310
PainD010146EFO_0003843R52—1—236
Migraine disordersD008881EFO_0003821G43———426
AnalgesiaD000698———1—236
Low back painD017116—M54.5——14—5
HeadacheD006261—R51———325
Renal colicD056844EFO_1001412N23———314
ColicD003085—R10.83———314
Back painD001416—M54———4—4
Show 32 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rib fracturesD012253———11—12
HysteroscopyD015907————1——1
Diabetic footD017719EFO_1001459———1——1
UlcerD014456MPATH_579———1——1
Foot ulcerD016523————1——1
Alveolar bone lossD016301————1——1
Chest painD002637—R07.9—11——1
Wounds and injuriesD014947—T14.8——1——1
Traumatic brain injuriesD000070642—S06——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Shoulder painD020069—M25.51—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Nerve blockD009407——————44
Impacted toothD014095—K01.1————33
Pain managementD059408——————33
Inguinal herniaD006552HP_0000023K40————22
HerniaD006547—K40-K46————22
EmergenciesD004630——————22
Laparoscopic cholecystectomyD017081——————22
Knee osteoarthritisD020370EFO_0004616M17————11
OsteoarthritisD010003EFO_0002506M15-M19————11
Maxillofacial injuriesD008446——————11
Show 38 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDexketoprofen
INNdexketoprofen
Description
Dexketoprofen is a monocarboxylic acid that is (S)-hydratropic acid substituted at position 3 on the phenyl ring by a benzoyl group. A cyclooxygenase inhibitor, it is used to relieve short-term pain, such as muscular pain, dental pain and dysmenorrhoea. It has a role as a non-steroidal anti-inflammatory drug, a cyclooxygenase 1 inhibitor, a cyclooxygenase 2 inhibitor and a non-narcotic analgesic. It is a monocarboxylic acid and a member of benzophenones. It is functionally related to a (S)-hydratropic acid.
Classification
Small molecule
Drug classanti-inflammatory/analgesic agents (ibuprofen type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C[C@H](C(=O)O)c1cccc(C(=O)c2ccccc2)c1
Identifiers
PDB—
CAS-ID22161-81-5
RxCUI—
ChEMBL IDCHEMBL75435
ChEBI ID76128
PubChem CID667550
DrugBankDB09214
UNII ID6KD9E78X68 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
Black-box warning for: Ketoprofen, Kiprofen
Adverse Events
Top Adverse Reactions
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891 adverse events reported
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