Dexibuprofen
Dexibuprofen is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| neoprofen | New Drug Application | 2023-11-02 |
Indications
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Clinical
Clinical Trials
932 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 14 | 15 | 25 | 34 | 24 | 111 |
| Postoperative pain | D010149 | — | G89.18 | 6 | 12 | 15 | 32 | 29 | 91 |
| Healthy volunteers/patients | — | — | — | 45 | — | — | 3 | 2 | 50 |
| Patent ductus arteriosus | D004374 | HP_0001643 | Q25.0 | 2 | 13 | 12 | 9 | 17 | 49 |
| Low back pain | D017116 | HP_0003419 | M54.5 | — | 3 | 5 | 13 | 7 | 27 |
| Acute pain | D059787 | — | R52 | 3 | 3 | 5 | 9 | 6 | 26 |
| Fever | D005334 | HP_0001945 | R50.9 | 2 | 1 | 5 | 11 | 4 | 23 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 3 | 3 | 7 | 5 | 2 | 20 |
| Analgesia | D000698 | — | — | — | 3 | 7 | 9 | 3 | 20 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 3 | — | 6 | 7 | 18 |
Show 107 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | 1 | — | 4 | 6 |
| Neoplasms | D009369 | — | C80 | — | 3 | 2 | — | 1 | 6 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | — | 1 | — | 4 | 5 |
| Breast diseases | D001941 | — | N60-N65 | — | — | 1 | — | 3 | 4 |
| Local anesthesia | D000772 | — | — | — | 2 | 1 | — | 2 | 4 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 3 | 1 | — | — | 3 |
| Cachexia | D002100 | HP_0004326 | R64 | — | 1 | 1 | — | 1 | 3 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | 1 | — | 1 | — | 1 | 3 |
| Altitude sickness | D000532 | EFO_1000782 | T70.29 | 1 | — | 1 | — | 1 | 3 |
| Impacted tooth | D014095 | HP_0011079 | K01.1 | — | 1 | 2 | — | 1 | 3 |
Show 46 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Foot and mouth disease hand | D006232 | EFO_0007294 | B08.4 | — | 1 | — | — | 4 | 5 |
| Malaria | D008288 | EFO_0001068 | B54 | 1 | 2 | — | — | 1 | 3 |
| Phimosis | D010688 | EFO_1001104 | N47.1 | 1 | 1 | — | — | — | 2 |
| Paraphimosis | D010263 | EFO_1001086 | N47.2 | 1 | 1 | — | — | — | 2 |
| Balanitis | D001446 | EFO_1000833 | N48.1 | 1 | 1 | — | — | — | 2 |
| Retinopathy of prematurity | D012178 | EFO_1001158 | H35.1 | — | 1 | — | — | 1 | 2 |
| Toothache | D014098 | — | K08.89 | 1 | 1 | — | — | 1 | 2 |
| Facial pain | D005157 | — | R51.9 | 1 | 1 | — | — | — | 2 |
| Leiomyoma | D007889 | HP_0000131 | D25 | — | 1 | — | — | 1 | 2 |
| Abdominal hernia | D046449 | — | K46 | — | 1 | — | — | 1 | 2 |
Show 48 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 5 | — | — | — | — | 5 |
| Drug interactions | D004347 | — | — | 1 | — | — | — | 1 | 2 |
| Thyroid diseases | D013959 | HP_0000820 | E00-E07 | 1 | — | — | — | 1 | 2 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | 1 | 2 |
| Pure autonomic failure | D054970 | — | — | 1 | — | — | — | — | 1 |
| Orthostatic hypotension | D007024 | — | I95.1 | 1 | — | — | — | — | 1 |
| Hematologic neoplasms | D019337 | — | — | 1 | — | — | — | — | 1 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 1 | — | — | — | — | 1 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 1 | — | — | — | — | 1 |
| Hodgkin disease | D006689 | — | C81 | 1 | — | — | — | — | 1 |
Show 12 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pelvic pain | D017699 | — | — | — | — | — | — | 5 | 5 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 3 | 3 |
| Cholecystitis | D002764 | HP_0001082 | K81 | — | — | — | — | 3 | 3 |
| Male breast neoplasms | D018567 | — | — | — | — | — | — | 2 | 2 |
| Prolapse | D011391 | — | — | — | — | — | — | 2 | 2 |
| Pneumonia | D011014 | EFO_0003106 | — | — | — | — | — | 2 | 2 |
| Laparoscopic cholecystectomy | D017081 | — | — | — | — | — | — | 2 | 2 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | — | — | 2 | 2 |
| Osteoporosis | D010024 | HP_0000939 | M81.0 | — | — | — | — | 2 | 2 |
| Aging | D000375 | GO_0007568 | R41.81 | — | — | — | — | 2 | 2 |
Show 88 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Dexibuprofen |
| INN | dexibuprofen |
| Description | Dexibuprofen is an ibuprofen. It has a role as a non-narcotic analgesic and a non-steroidal anti-inflammatory drug. It is an enantiomer of a levibuprofen. |
| Classification | Small molecule |
| Drug class | anti-inflammatory/analgesic agents (ibuprofen type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)Cc1ccc([C@H](C)C(=O)O)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 51146-56-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL175 |
| ChEBI ID | 43415 |
| PubChem CID | 39912 |
| DrugBank | — |
| UNII ID | 671DKG7P5S (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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1,389 adverse events reported
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