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Drug ReportsDesonide
Desonide
Desonide, Desowen, Tridesilon (desonide) is a small molecule pharmaceutical. Desonide was first approved as Tridesilon on 1982-01-01. It is used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, and leg dermatoses amongst others in the USA.
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Financial
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FDA approval date
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Study first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Desowen (generic drugs available since 1988-06-15, discontinued: Desonate, Verdeso)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetic acid
+
glacial
+
Desonide
Tradename
Company
Number
Date
Products
TRIDESILONBayerN-017914 DISCN1982-01-01
1 products
Hide discontinued
Desonide
Tradename
Company
Number
Date
Products
DESOWENGaldermaN-019048 RX1984-12-14
1 products
DESONIDEPadagisN-017010 RX1982-01-01
1 products, RLD, RS
DESONIDEPadagisN-017426 RX1982-01-01
1 products, RLD, RS
Show 2 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
desonateNew Drug Application2010-10-19
desonideANDA2024-01-31
desonide ointment, 0.05%ANDA2024-01-31
desowenANDA2018-01-03
lokaraANDA2013-11-22
verdesoNew Drug Application2021-08-01
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
facial dermatoses—D005148—
foot dermatoses—D005533—
hand dermatoses—D006229—
inflammationMP_0001845D007249—
leg dermatoses—D007868—
scalp dermatoses—D012536—
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Desonide, Verdeso, Almirall
84606412027-08-13DPU-1412
89620002025-08-31DPU-1412
94923842025-08-31DPU-1412
ATC Codes
D: Dermatologicals
— D07: Corticosteroids, dermatological preparations
— D07A: Corticosteroid dermatological preparations, plain
— D07AB: Corticosteroids, moderately potent (group ii)
— D07AB08: Desonide
— D07B: Corticosteroids, combinations with antiseptics
— D07BB: Corticosteroids, moderately potent, combinations with antiseptics
— D07BB02: Desonide and antiseptics
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01B: Antiinflammatory agents, ophthalmologic
— S01BA: Corticosteroid ophthalmologic antiinflammatory agents, plain
— S01BA11: Desonide
HCPCS
Code
Description
J7626
Budesonide, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, up to 0.5 mg
J7627
Budesonide, inhalation solution, compounded product, administered through dme, unit dose form, up to 0.5 mg
J7633
Budesonide, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, per 0.25 milligram
J7634
Budesonide, inhalation solution, compounded product, administered through dme, concentrated form, per 0.25 milligram
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atopic dermatitisD003876EFO_0000274L20——33—6
EczemaD004485HP_0000964L30.9——11—2
PsoriasisD011565EFO_0000676L40———1—1
HyperpigmentationD017495HP_0000953————1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———1————1
VasoconstrictionD014661——1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDesonide
INNdesonide
Description
Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. Other trade names for creams, lotions, and ointments include Tridesilon, DesOwen, Desonate. It is a group VI corticosteroid under US classification, the second least potent group.
Classification
Small molecule
Drug classtopical steroids (acetal derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
Identifiers
PDB—
CAS-ID638-94-8
RxCUI—
ChEMBL IDCHEMBL1201109
ChEBI ID204734
PubChem CID12536
DrugBankDB01260
UNII IDJ280872D1O (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Desonide
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 410 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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36,824 adverse events reported
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