Desogestrel
Bekyree, Cyclessa, Desogestrel / Ethinyl Estradiol, Enskyce, Isibloom, Kalliga, Kariva, Pimtrea, Simliya, Velivet, Viorele, Volnea (desogestrel) is a small molecule pharmaceutical. Desogestrel was first approved as Desogen on 1992-12-10. It is used to treat acne vulgaris, endometriosis, and menstruation disturbances in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Combinations
Averi, Bekyree, Cyclessa, Desogestrel ethinyl estradiol, Enskyce, Isibloom, Kalliga, Kariva, Pimtrea, Simliya, Velivet, Viorele, Volnea (discontinued: Desogen, Desogestrel ethinyl estradiol, Emoquette, Kimidess, Mircette, Ortho-cept)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Desogestrel
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Ethinyl estradiol
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CYCLESSA | Aspen Global | N-021090 RX | 2000-12-20 | 1 products, RLD, RS |
Show 3 discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03A: Hormonal contraceptives for systemic use
— G03AA: Progestogens and estrogen systemic contraceptives, fixed combinations
— G03AA09: Desogestrel and ethinylestradiol
— G03AB: Progestogens and estrogens systemic contraceptives, sequential preparations
— G03AB05: Desogestrel and ethinylestradiol
— G03AC: Progestogen systemic hormonal contraceptives
— G03AC09: Desogestrel
— G03F: Progestogens and estrogens in combination
— G03FB: Progestogens and estrogens, sequential preparations
— G03FB10: Desogestrel and estrogen
HCPCS
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Clinical
Clinical Trials
108 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | — | — | 1 | — | — | 1 |
| Contraception | D003267 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemostasis | D006487 | — | — | — | 2 | — | — | — | 2 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Desogestrel |
| INN | desogestrel |
| Description | Desogestrel is a 17beta-hydroxy steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin and a synthetic oral contraceptive. |
| Classification | Small molecule |
| Drug class | estrogens; progestins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3C(=C)C[C@@]21CC |
Identifiers
| PDB | — |
| CAS-ID | 54024-22-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1533 |
| ChEBI ID | 4453 |
| PubChem CID | 40973 |
| DrugBank | DB00304 |
| UNII ID | 81K9V7M3A3 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
Revenue by drug
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Estimated US medical usage
Desogestrel
+
Ethinyl estradiol
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,934 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,205 adverse events reported
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