Brand Name | Status | Last Update |
---|---|---|
clarinex | New Drug Application | 2022-11-14 |
clarinex-d 12 hour | New Drug Application | 2022-06-01 |
desloratadine | ANDA | 2024-01-19 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | 2 | 5 | 11 | 1 | 19 |
Allergic rhinitis | D065631 | — | J30.9 | — | — | 8 | 4 | — | 12 |
Urticaria | D014581 | EFO_0005531 | L50 | — | — | 2 | 7 | 3 | 12 |
Chronic urticaria | D000080223 | — | L50.8 | — | 2 | 2 | 4 | — | 8 |
Allergic rhinitis perennial | D012221 | EFO_1001417 | J30.89 | — | — | 2 | 4 | 1 | 7 |
Hypersensitivity | D006967 | HP_0012393 | T78.40 | 1 | 1 | 1 | 3 | 1 | 6 |
Asthma | D001249 | EFO_0000270 | J45 | — | — | 1 | 1 | 2 | 4 |
Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cold temperature | D003080 | — | — | — | — | 1 | — | — | 1 |
Eczema | D004485 | HP_0000964 | L30.9 | — | — | 1 | — | — | 1 |
Dermatitis | D003872 | HP_0011123 | L30.9 | — | — | 1 | — | — | 1 |
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | 1 | — | — | 1 |
Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | 1 | — | — | 1 |
Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | — | — | — | 1 |
Rhinorrhea | D000086722 | — | — | — | 1 | — | — | — | 1 |
Peanut hypersensitivity | D021183 | EFO_0007425 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 5 | — | — | — | — | 5 |
Fasting | D005215 | EFO_0002756 | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Rhinitis | D012220 | EFO_0008521 | J31 | — | — | — | — | 4 | 4 |
Pruritus | D011537 | HP_0000989 | L29 | — | — | — | — | 2 | 2 |
Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
Heat stress disorders | D018882 | — | T67.2 | — | — | — | — | 1 | 1 |
Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 1 | 1 |
Drug common name | Desloratadine |
INN | desloratadine |
Description | Desloratadine is loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. It has a role as a H1-receptor antagonist, an anti-allergic agent, a cholinergic antagonist and a drug metabolite. |
Classification | Small molecule |
Drug class | tricyclic histaminic-H1 receptor antagonists, loratadine derivatives (formerly-tadine) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Clc1ccc2c(c1)CCc1cccnc1C2=C1CCNCC1 |
PDB | — |
CAS-ID | 100643-71-8 |
RxCUI | — |
ChEMBL ID | CHEMBL1172 |
ChEBI ID | 291342 |
PubChem CID | 124087 |
DrugBank | DB00967 |
UNII ID | FVF865388R (ChemIDplus, GSRS) |