Desflurane
Desflurane, Suprane (desflurane) is a small molecule pharmaceutical. Desflurane was first approved as Suprane on 1992-09-18. It is used to treat pain in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Desflurane, Suprane
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| desflurane | unapproved drug other | 2026-07-08 |
| suprane | New Drug Application | 2026-07-15 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| pain | EFO_0003843 | D010146 | R52 |
Agency Specific
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Clinical
Clinical Trials
326 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anesthesia | D000758 | — | — | — | 1 | 4 | 12 | 31 | 47 |
| General anesthesia | D000768 | — | — | 1 | 1 | 1 | 4 | 15 | 21 |
| Emergence delirium | D000071257 | — | — | — | — | — | 7 | 9 | 16 |
| Delirium | D003693 | — | R41.0 | — | — | — | 5 | 8 | 13 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | 6 | 4 | 11 |
| Postoperative cognitive complications | D000079690 | — | — | 1 | 1 | — | 3 | 7 | 11 |
| Postoperative pain | D010149 | — | G89.18 | — | 1 | 1 | 2 | 5 | 9 |
| Cognitive dysfunction | D060825 | — | G31.84 | 1 | 1 | — | 2 | 6 | 9 |
| Respiratory aspiration | D053120 | EFO_1001839 | — | — | — | — | 1 | 6 | 7 |
| Cough | D003371 | — | R05 | — | — | — | 2 | 5 | 7 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatectomy | D006498 | — | — | 1 | — | 1 | — | — | 2 |
| Musculoskeletal diseases | D009140 | — | — | — | — | 1 | — | — | 1 |
| Cystoscopes | D020684 | — | — | — | — | 1 | — | — | 1 |
| Cognition | D003071 | EFO_0003925 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Replacement arthroplasty knee | D019645 | — | — | — | 1 | — | — | 2 | 3 |
| Kidney transplantation | D016030 | — | — | — | 1 | — | — | 1 | 2 |
| Orthopedic procedures | D019637 | — | — | — | 1 | — | — | — | 1 |
| Hip prosthesis | D006622 | — | — | — | 1 | — | — | — | 1 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Reperfusion injury | D015427 | — | — | — | — | — | — | 3 | 3 |
| Laparoscopic cholecystectomy | D017081 | — | — | — | — | — | — | 3 | 3 |
| Pain management | D059408 | — | — | — | — | — | — | 2 | 2 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | — | 2 | 2 |
| Urologic diseases | D014570 | — | N39.9 | — | — | — | — | 2 | 2 |
| Cognition disorders | D003072 | — | — | — | — | — | — | 2 | 2 |
| Lung injury | D055370 | — | S27.30 | — | — | — | — | 2 | 2 |
| Neuromuscular monitoring | D061886 | — | — | — | — | — | — | 2 | 2 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | — | — | — | 2 | 2 |
| Robotic surgical procedures | D065287 | — | — | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Desflurane |
| INN | desflurane |
| Description | Desflurane is an organofluorine compound. It has a role as an inhalation anaesthetic. It is functionally related to a methoxyethane. |
| Classification | Small molecule |
| Drug class | general inhalation anesthetics (halogenated alkane derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | FC(F)OC(F)C(F)(F)F |
Identifiers
| PDB | — |
| CAS-ID | 57041-67-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200733 |
| ChEBI ID | 4445 |
| PubChem CID | 42113 |
| DrugBank | DB01189 |
| UNII ID | CRS35BZ94Q (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,266 adverse events reported
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