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Drug ReportsDeserpidine
Deserpidine
Enduronyl, Harmonyl, Oreticyl (deserpidine) is a small molecule pharmaceutical. Deserpidine was first approved as Harmonyl on 1982-01-01. It is used to treat dyskinesias, hypertension, and schizophrenia in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
mental disordersD001523
Trade Name
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EMA
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Deserpidine
Tradename
Company
Number
Date
Products
HARMONYLAbbVieN-010796 DISCN1982-01-01
2 products
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Deserpidine
+
Hydrochlorothiazide
Tradename
Company
Number
Date
Products
ORETICYL 25AbbVieN-012148 DISCN1982-01-01
1 products
ORETICYL FORTEAbbVieN-012148 DISCN1982-01-01
1 products
ORETICYL 50AbbVieN-012148 DISCN1982-01-01
1 products
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Deserpidine
+
Methyclothiazide
Tradename
Company
Number
Date
Products
ENDURONYLAbbott BiotherapeuticsN-012775 DISCN1982-01-01
1 products
ENDURONYL FORTEAbbott BiotherapeuticsN-012775 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
C02: Antihypertensives
C02A: Antiadrenergic agents, centrally acting
C02AA: Rauwolfia alkaloids, centrally acting antiadrenergic
C02AA05: Deserpidine
C02L: Antihypertensives and diuretics in combination
C02LA: Rauwolfia alkaloids and diuretics in combination
C02LA03: Deserpidine and diuretics
HCPCS
No data
Clinical
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Drug
General
Drug common nameDeserpidine
INNdeserpidine
Description
Deserpidine is an alkaloid ester, a methyl ester, a benzoate ester, an organic heteropentacyclic compound and a yohimban alkaloid. It derives from a hydride of a yohimban.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5ccccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
Identifiers
PDB
CAS-ID131-01-1
RxCUI
ChEMBL IDCHEMBL1200515
ChEBI ID27478
PubChem CID8550
DrugBankDB01089
UNII ID9016E3VB47 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
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Estimated US medical usage
Deserpidine
+
Methyclothiazide
Total medical expenditures per year (USD, in millions)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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