Brand Name | Status | Last Update |
---|---|---|
deferoxamine | ANDA | 2025-03-20 |
deferoxamine mesylate | ANDA | 2025-09-17 |
desferal | New Drug Application | 2025-06-17 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
bone diseases | — | D001847 | M89.9 |
corneal diseases | — | D003316 | H18.9 |
hemochromatosis | EFO_1000642 | D006432 | E83.11 |
Code | Description |
---|---|
J0895 | Injection, deferoxamine mesylate, 500 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Iron overload | D019190 | — | — | 1 | 15 | 5 | 3 | 5 | 25 |
Thalassemia | D013789 | EFO_1001996 | D56 | 2 | 11 | 4 | 5 | 6 | 25 |
Beta-thalassemia | D017086 | Orphanet_848 | D56.1 | 1 | 9 | 5 | 5 | 4 | 21 |
Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | 6 | 1 | 3 | — | 9 |
Hemochromatosis | D006432 | EFO_1000642 | E83.11 | — | 4 | 3 | 2 | 1 | 9 |
Hemosiderosis | D006486 | — | — | — | 4 | 3 | 2 | 1 | 9 |
Anemia | D000740 | EFO_0004272 | D64.9 | — | 3 | — | 2 | 1 | 6 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | — | 1 | 2 | 4 |
Covid-19 | D000086382 | — | U07.1 | 1 | 1 | 1 | 1 | — | 3 |
Cardiomyopathies | D009202 | EFO_0000318 | I42 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cerebral hemorrhage | D002543 | — | — | 2 | 4 | 1 | — | — | 6 |
Stroke | D020521 | EFO_0000712 | I63.9 | 1 | 1 | 2 | — | — | 4 |
Hemorrhage | D006470 | MP_0001914 | R58 | 2 | 2 | 1 | — | — | 4 |
Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | 1 | 2 | 1 | — | — | 3 |
Carcinoma | D002277 | — | C80.0 | 1 | — | 1 | — | — | 2 |
Oxidative stress | D018384 | EFO_1001905 | — | — | 1 | 1 | — | — | 1 |
Renal cell carcinoma | D002292 | EFO_0000376 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 5 | 1 | — | — | — | 5 |
Myelodysplastic syndromes | D009190 | — | D46 | — | 2 | — | — | 2 | 4 |
Preleukemia | D011289 | — | — | — | 1 | — | — | 2 | 3 |
Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | 2 | — | — | 1 | 3 |
Subarachnoid hemorrhage | D013345 | EFO_0000713 | I60 | 2 | 2 | — | — | — | 3 |
Syndrome | D013577 | — | — | — | 1 | — | — | 1 | 2 |
Ulcer | D014456 | MPATH_579 | — | 1 | 2 | — | — | — | 2 |
Ischemic stroke | D000083242 | — | — | — | 1 | — | — | 1 | 2 |
Ischemia | D007511 | EFO_0000556 | — | 1 | 1 | — | — | — | 2 |
Acute kidney injury | D058186 | — | N17 | — | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasm metastasis | D009362 | EFO_0009708 | — | 3 | — | — | — | — | 3 |
Lymphoma | D008223 | — | C85.9 | 2 | — | — | — | — | 2 |
Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
B-cell lymphoma | D016393 | — | — | 1 | — | — | — | — | 1 |
Meningeal carcinomatosis | D055756 | EFO_1001012 | — | 1 | — | — | — | — | 1 |
Cardiac arrhythmias | D001145 | EFO_0004269 | I49.9 | 1 | — | — | — | — | 1 |
Reperfusion injury | D015427 | — | — | 1 | — | — | — | — | 1 |
Myocardial reperfusion injury | D015428 | EFO_0002687 | — | 1 | — | — | — | — | 1 |
Inferior wall myocardial infarction | D056989 | EFO_1000983 | — | 1 | — | — | — | — | 1 |
Castration-resistant prostatic neoplasms | D064129 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | — | — | — | — | 1 | 1 |
Osteoporosis | D010024 | EFO_0003882 | M81.0 | — | — | — | — | 1 | 1 |
Chelation therapy | D015913 | — | — | — | — | — | — | 1 | 1 |
Leukemia | D007938 | — | C95 | — | — | — | — | 1 | 1 |
Myeloid leukemia acute | D015470 | — | C92.0 | — | — | — | — | 1 | 1 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | — | — | — | 1 | 1 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 1 | 1 |
Brain ischemia | D002545 | EFO_0003883 | I67.82 | — | — | — | — | 1 | 1 |
Drug common name | Deferoxamine |
INN | deferoxamine |
Description | Deferoxamine (DFOA), also known as desferrioxamine and sold under the brand name Desferal, is a medication that binds iron and aluminium. It is specifically used in iron overdose, hemochromatosis either due to multiple blood transfusions or an underlying genetic condition, and aluminium toxicity in people on dialysis. It is used by injection into a muscle, vein, or under the skin.
|
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN |
PDB | — |
CAS-ID | 70-51-9 |
RxCUI | — |
ChEMBL ID | CHEMBL556 |
ChEBI ID | 4356 |
PubChem CID | 2973 |
DrugBank | DB00746 |
UNII ID | J06Y7MXW4D (ChemIDplus, GSRS) |