Darovasertib
Darovasertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target protein kinase C alpha type and protein kinase C theta type.
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Commercial
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Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uveal neoplasms | D014604 | EFO_1001230 | — | 1 | 3 | 2 | — | — | 4 |
| Uveal melanoma | D000098943 | — | — | 1 | 3 | 2 | — | — | 4 |
| Melanoma | D008545 | — | — | 1 | 2 | 2 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | 1 | — | — | — | 1 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 1 |
| Cutaneous malignant melanoma | D000096142 | — | — | 1 | 1 | — | — | — | 1 |
| Amyloid plaque | D058225 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Darovasertib |
| INN | darovasertib |
| Description | Darovasertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target protein kinase C alpha type and protein kinase C theta type. |
| Classification | Small molecule |
| Drug class | serine/threonine kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3ncccc3C(F)(F)F)cnc2N)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1874276-76-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3982723 |
| ChEBI ID | — |
| PubChem CID | 118873253 |
| DrugBank | DB16059 |
| UNII ID | E0YF0M8O09 (ChemIDplus, GSRS) |
Target
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Safety
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22 adverse events reported
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