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AboutPricing
Drug ReportsDaptomycin
Cubicin(daptomycin)
Cubicin, Daptomycin (daptomycin) is a protein pharmaceutical. Daptomycin was first approved as Cubicin on 2003-09-12. It is used to treat bacteremia, bacterial infections, and bacterial skin diseases in the USA. It has been approved in Europe to treat bacteremia, bacterial endocarditis, bacterial skin diseases, gram-positive bacterial infections, and soft tissue infections.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Daptomycin (discontinued: Cubicin rf, Daptomycin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Daptomycin
Tradename
Company
Number
Date
Products
DAPTOMYCIN IN 0.9% SODIUM CHLORIDEBaxterN-213645 RX2023-02-27
4 products, RLD, RS
DAPTOMYCINHospiraN-210282 RX2021-06-21
2 products, RLD, RS
DAPTOMYCINSagent PharmaceuticalsN-208385 RX2017-09-12
1 products, RLD, RS
DAPTOMYCINXelliaN-209949 RX2017-10-20
1 products, RLD, RS
DAPTOMYCINXelliaN-217415 RX2023-01-30
2 products, RLD, RS
Show 3 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
cubicinExport only2024-10-14
cubicin rfNew Drug Application2024-10-16
daptomycinANDA2024-11-06
daptomycin in sodium chlorideNew Drug Application2023-02-27
dapzura rtNew Drug Application2022-01-25
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial skin diseases—D017192—
bacteremiaEFO_0003033D016470R78.81
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Daptomycin, Daptomycin In 0.9% Sodium Chloride, Baxter Hlthcare Corp
111731892041-03-11DPU-3294
Daptomycin, Daptomycin, Xellia Pharms Aps
117594972038-08-28DP
Daptomycin, Daptomycin, Hospira
96559462033-09-11DPU-3175
103575352033-09-11DPU-3176
Daptomycin, Cubicin, Cubist Pharms Llc
91384562030-11-23DP
80036732028-09-04U-1180
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01X: Other antibacterials in atc
— J01XX: Other antibacterials in atc
— J01XX09: Daptomycin
HCPCS
Code
Description
J0877
Injection, daptomycin (hospira), not therapeutically equivalent to j0878, 1 mg
J0878
Injection, daptomycin, 1 mg
Clinical
No data
Drug
General
Drug common nameDaptomycin
INNdaptomycin
Description
Daptomycin, sold under the brand name Cubicin among others, is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms.
Classification
Small molecule
Drug classaptamers, classical and mirror; antibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]1C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H]([C@H](C)CC(=O)O)C(=O)N[C@@H](CC(=O)c2ccccc2N)C(=O)O[C@@H]1C
Identifiers
PDB—
CAS-ID103060-53-3
RxCUI—
ChEMBL IDCHEMBL387675
ChEBI ID600103
PubChem CID16129629
DrugBankDB00080
UNII IDNWQ5N31VKK (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Cubicin – Merck & Co
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Estimated US medical usage
Daptomycin
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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