Dapiprazole
Dapiprazole is a small molecule pharmaceutical. Dapiprazole was first approved as Dapiprazole hydrochloride on 1990-12-31. It is used to treat mydriasis in the USA. The pharmaceutical is active against alpha-1D adrenergic receptor.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dapiprazole hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DAPIPRAZOLE HYDROCHLORIDE | Fera Pharmaceuticals | N-019849 DISCN | 1990-12-31 | 1 products, RLD |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| dapiprazole | ANDA | 2024-01-09 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| mydriasis | HP_0011499 | D015878 | H57.04 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
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Clinical
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Drug
General
| Drug common name | Dapiprazole |
| INN | dapiprazole |
| Description | Dapiprazole is a N-arylpiperazine, a N-alkylpiperazine and a member of pyridines. It has a role as an alpha-adrenergic antagonist, a miotic, an ophthalmology drug and an antipsychotic agent. |
| Classification | Small molecule |
| Drug class | antiulcer agents (benzimidazole derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ccccc1N1CCN(CCc2nnc3n2CCCC3)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 72822-12-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201216 |
| ChEBI ID | 51066 |
| PubChem CID | 3033538 |
| DrugBank | DB00298 |
| UNII ID | 5RNZ8GJO7K (ChemIDplus, GSRS) |
Target
Agency Approved
ADRA1D
ADRA1D
Organism
Homo sapiens
Gene name
ADRA1D
Gene synonyms
ADRA1A
NCBI Gene ID
Protein name
alpha-1D adrenergic receptor
Protein synonyms
adrenergic, alpha -1D-, receptor, adrenergic, alpha-1A-, receptor, Alpha-1A adrenergic receptor, Alpha-1D adrenoceptor, Alpha-1D adrenoreceptor, Alpha-adrenergic receptor 1a
Uniprot ID
Mouse ortholog
Adra1d (11550)
alpha-1D adrenergic receptor (Q61619)
Alternate
No data
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Financial
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PubMed Central
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Safety
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Adverse Events
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