Dapiprazole
Dapiprazole is a small molecule pharmaceutical. Dapiprazole was first approved as Dapiprazole hydrochloride on 1990-12-31. It is used to treat mydriasis in the USA. The pharmaceutical is active against alpha-1D adrenergic receptor.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dapiprazole hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DAPIPRAZOLE HYDROCHLORIDE | Fera Pharmaceuticals | N-019849 DISCN | 1990-12-31 | 1 products, RLD |
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| dapiprazole | ANDA | 2024-01-09 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
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Clinical
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Drug
General
| Drug common name | Dapiprazole |
| INN | dapiprazole |
| Description | Dapiprazole is a N-arylpiperazine, a N-alkylpiperazine and a member of pyridines. It has a role as an alpha-adrenergic antagonist, a miotic, an ophthalmology drug and an antipsychotic agent. |
| Classification | Small molecule |
| Drug class | antiulcer agents (benzimidazole derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ccccc1N1CCN(CCc2nnc3n2CCCC3)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 72822-12-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201216 |
| ChEBI ID | 51066 |
| PubChem CID | 3033538 |
| DrugBank | DB00298 |
| UNII ID | 5RNZ8GJO7K (ChemIDplus, GSRS) |
Target
Agency Approved
ADRA1D
ADRA1D
Organism
Homo sapiens
Gene name
ADRA1D
Gene synonyms
ADRA1A
NCBI Gene ID
Protein name
alpha-1D adrenergic receptor
Protein synonyms
adrenergic, alpha -1D-, receptor, adrenergic, alpha-1A-, receptor, Alpha-1A adrenergic receptor, Alpha-1D adrenoceptor, Alpha-1D adrenoreceptor, Alpha-adrenergic receptor 1a
Uniprot ID
Mouse ortholog
Adra1d (11550)
alpha-1D adrenergic receptor (Q61619)
Alternate
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Safety
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