Danaparoid sodium
Orgaran (danaparoid sodium) is an unknown pharmaceutical. Danaparoid sodium was first approved as Orgaran on 1996-12-24. It is used to treat pulmonary embolism, thrombocytopenia, thromboembolism, and venous thrombosis in the USA. The pharmaceutical is active against antithrombin-III.
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Danaparoid sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ORGARAN | Aspen Global | N-020430 DISCN | 1996-12-24 | 1 products |
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6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | — | 1 | — | 2 | 3 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 2 | 2 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | — | — | 1 | 1 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | — | — | — | 1 | 1 |
| Thrombosis | D013927 | — | — | — | — | — | — | 1 | 1 |
| Thromboembolism | D013923 | HP_0001907 | — | — | — | — | — | 1 | 1 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | — | — | 1 | 1 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.9 | — | — | — | — | 1 | 1 |
| Renal insufficiency | D051437 | HP_0000083 | N19 | — | — | — | — | 1 | 1 |
| Ischemic stroke | D000083242 | — | — | — | — | — | — | 1 | 1 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Danaparoid sodium |
| INN | danaparoid sodium |
| Description | Orgaran (danaparoid sodium) is an unknown pharmaceutical. Danaparoid sodium was first approved as Orgaran on 1996-12-24. It is used to treat pulmonary embolism, thrombocytopenia, thromboembolism, and venous thrombosis in the USA. The pharmaceutical is active against antithrombin-III. |
| Classification | Small molecule |
| Drug class | antithrombotics (heparinoid type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 308068-55-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201534 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB06754 |
| UNII ID | 5004UU3156 (ChemIDplus, GSRS) |
Target
Agency Approved
SERPINC1
SERPINC1
Organism
Homo sapiens
Gene name
SERPINC1
Gene synonyms
AT3
NCBI Gene ID
Protein name
antithrombin-III
Protein synonyms
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, Serpin C1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Uniprot ID
Mouse ortholog
Serpinc1 (11905)
antithrombin-III (P32261)
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724 adverse events reported
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