Brand Name | Status | Last Update |
---|---|---|
ampyra | New Drug Application | 2025-05-05 |
dalfampridine | ANDA | 2025-07-28 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
multiple sclerosis | EFO_0003885 | D009103 | G35 |
neurologic gait disorders | — | D020233 | R26.1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 10 | 14 | 9 | 11 | 40 |
Sclerosis | D012598 | — | — | — | 10 | 14 | 8 | 8 | 36 |
Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | 1 | 5 | 1 | — | 6 |
Whooping cough | D014917 | EFO_0000650 | A37 | 2 | — | 2 | 1 | 1 | 6 |
Diphtheria | D004165 | EFO_0005549 | A36 | 1 | — | 2 | 1 | — | 4 |
Malaria | D008288 | EFO_0001068 | B54 | 1 | — | — | 2 | — | 3 |
Tetanus | D013742 | EFO_0005593 | A35 | 1 | — | 1 | 1 | — | 3 |
Poliomyelitis | D011051 | EFO_0007450 | A80 | — | — | 2 | 1 | — | 3 |
Falciparum malaria | D016778 | EFO_0007444 | B50 | 1 | — | — | 1 | — | 2 |
Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Wounds and injuries | D014947 | — | T14.8 | 1 | 6 | 4 | — | — | 9 |
Infections | D007239 | EFO_0000544 | — | — | 1 | 5 | — | 1 | 6 |
Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | 1 | 6 | — | — | 6 |
Spinal cord injuries | D013119 | EFO_1001919 | — | 2 | 2 | 3 | — | — | 6 |
Neoplasms | D009369 | — | C80 | 3 | 2 | 1 | — | 1 | 6 |
Communicable diseases | D003141 | — | — | — | 1 | 4 | — | 1 | 5 |
Fatigue | D005221 | — | R53.83 | — | 3 | 1 | — | 1 | 4 |
Peripheral nerve injuries | D059348 | — | — | — | 3 | 2 | — | — | 3 |
Ischemic stroke | D000083242 | — | — | — | 1 | 2 | — | — | 3 |
Muscle spasticity | D009128 | — | — | — | — | 2 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | 3 | 4 | — | — | — | 6 |
Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 1 | 3 | — | — | — | 4 |
Myeloid leukemia | D007951 | — | C92 | 1 | 3 | — | — | — | 4 |
Short-term memory | D008570 | EFO_0004335 | — | — | 3 | — | — | 1 | 4 |
Syndrome | D013577 | — | — | 1 | 2 | — | — | 2 | 4 |
Myeloid leukemia accelerated phase | D015465 | — | — | 1 | 2 | — | — | — | 3 |
Blast crisis | D001752 | — | — | 1 | 2 | — | — | — | 3 |
Non-small-cell lung carcinoma | D002289 | — | — | 1 | 1 | — | — | 1 | 3 |
Recurrence | D012008 | — | — | 2 | 1 | — | — | — | 3 |
Carcinoma | D002277 | — | C80.0 | 1 | 2 | — | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | 9 | 10 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | — | — | — | 6 | 7 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | 2 | 3 |
Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | — | — | — | 2 | 3 |
Periapical periodontitis | D010485 | EFO_1001391 | K04.5 | 1 | — | — | — | 2 | 3 |
Cerebral palsy | D002547 | — | G80 | 1 | — | — | — | 1 | 2 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | 1 | 2 |
Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | 1 | — | — | — | — | 1 |
Motor neuron disease | D016472 | EFO_0003782 | G12.2 | 1 | — | — | — | — | 1 |
Trismus | D014313 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | — | 3 | 3 |
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 2 | 2 |
Peripheral nervous system diseases | D010523 | — | G64 | — | — | — | — | 2 | 2 |
Hypoglycemia | D007003 | — | E16.2 | — | — | — | — | 2 | 2 |
Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | — | — | 2 | 2 |
Dermatitis | D003872 | — | L30.9 | — | — | — | — | 2 | 2 |
Patellofemoral pain syndrome | D046788 | EFO_1001092 | — | — | — | — | — | 2 | 2 |
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | — | — | — | 2 | 2 |
Traumatic stress disorders | D040921 | — | — | — | — | — | — | 2 | 2 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 2 | 2 |
Drug common name | Dalfampridine |
INN | fampridine |
Description | 4-aminopyridine is an aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis. It has a role as an avicide, a potassium channel blocker and an orphan drug. It is an aromatic amine and an aminopyridine. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Nc1ccncc1 |
PDB | — |
CAS-ID | 504-24-5 |
RxCUI | — |
ChEMBL ID | CHEMBL284348 |
ChEBI ID | 34385 |
PubChem CID | 1727 |
DrugBank | DB06637 |
UNII ID | BH3B64OKL9 (ChemIDplus, GSRS) |