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Drug ReportsDERENOFYLLINE
DERENOFYLLINE
Derenofylline is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target adenosine receptor A2a, adenosine receptor A3, adenosine receptor A2b, and adenosine receptor A1.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart failureD006333EFO_0003144I50—2——13
Renal insufficiencyD051437—N19—1——12
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDERENOFYLLINE
INNderenofylline
Description
Derenofylline is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target adenosine receptor A2a, adenosine receptor A3, adenosine receptor A2b, and adenosine receptor A1.
Classification
Small molecule
Drug classtheophylline derivatives
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Structure (InChI/SMILES or Protein Sequence)
OC1CCC(Nc2nc(-c3ccccc3)nc3[nH]ccc23)CC1
Identifiers
PDB—
CAS-ID1990532-34-7
RxCUI—
ChEMBL IDCHEMBL592435
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDO1Q96UZ63W (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ADORA3
ADORA3
Organism
Homo sapiens
Gene name
ADORA3
Gene synonyms
NCBI Gene ID
Protein name
adenosine receptor A3
Protein synonyms
Uniprot ID
Mouse ortholog
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—
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 61 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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