DACETUZUMAB
Dacetuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target tumor necrosis factor receptor superfamily member 5.
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Events Timeline
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YTD
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5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 3 | 2 | — | — | — | 5 |
| Lymphoma | D008223 | — | C85.9 | 3 | 2 | — | — | — | 5 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | 2 | — | — | — | 3 |
| Leukemia | D007938 | — | C95 | 1 | 1 | — | — | — | 1 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 1 | 1 | — | — | — | 1 |
| Lymphoid leukemia | D007945 | — | C91 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 3 | — | — | — | — | 3 |
| Plasma cell neoplasms | D054219 | — | — | 3 | — | — | — | — | 3 |
| B-cell lymphoma | D016393 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | DACETUZUMAB |
| INN | dacetuzumab |
| Description | Dacetuzumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1743005 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | UT59FF4T5X (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CD40
CD40
Organism
Homo sapiens
Gene name
CD40
Gene synonyms
TNFRSF5
NCBI Gene ID
Protein name
tumor necrosis factor receptor superfamily member 5
Protein synonyms
B cell surface antigen CD40, B cell-associated molecule, B-cell surface antigen CD40, Bp50, CD40, CD40 molecule, TNF receptor superfamily member 5, CD40L receptor, CDw40
Uniprot ID
Mouse ortholog
Cd40 (21939)
tumor necrosis factor receptor superfamily member 5 (Q99NE3)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 279 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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23 adverse events reported
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