Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PERIACTIN | Merck KGaA | N-012649 DISCN | 1982-01-01 | 1 products, RLD |
PERIACTIN | Merck KGaA | N-013220 DISCN | 1982-01-01 | 1 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
cyproheptadine | ANDA | 2023-10-05 |
cyproheptadine hydrochloride | ANDA | 2024-01-17 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Feeding behavior | D005247 | — | — | — | — | — | 1 | — | 1 |
Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | — | — | 1 | — | 1 |
Neurodevelopmental disorders | D065886 | — | F89 | — | — | — | 1 | — | 1 |
Attention deficit and disruptive behavior disorders | D019958 | HP_0010865 | F91.3 | — | — | — | 1 | — | 1 |
Failure to thrive | D005183 | — | — | — | — | — | 1 | — | 1 |
Treatment outcome | D016896 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | — | 2 | 1 | — | — | 3 |
Viral pneumonia | D011024 | EFO_0007541 | J12.9 | — | 1 | 1 | — | — | 2 |
Serotonin syndrome | D020230 | EFO_1001842 | — | — | 1 | 1 | — | — | 2 |
Pneumonia | D011014 | EFO_0003106 | — | — | 1 | 1 | — | — | 2 |
Chronic urticaria | D000080223 | — | L50.8 | — | — | 1 | — | — | 1 |
Anorexia | D000855 | HP_0002039 | R63.0 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 2 | — | — | — | 2 |
Leukemia | D007938 | — | C95 | — | 2 | — | — | — | 2 |
Myelodysplastic syndromes | D009190 | — | D46 | — | 2 | — | — | — | 2 |
Lymphoma | D008223 | — | C85.9 | — | 2 | — | — | — | 2 |
Covid-19 | D000086382 | — | U07.1 | — | 1 | — | — | — | 1 |
Abdominal pain | D015746 | HP_0002027 | R10.9 | — | 1 | — | — | — | 1 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 1 | — | — | — | 1 |
Body weight changes | D001836 | — | — | — | 1 | — | — | — | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 1 | — | — | — | 1 |
Myelodysplastic-myeloproliferative diseases | D054437 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Spinal cord injuries | D013119 | EFO_1001919 | — | 1 | — | — | — | 2 | 3 |
Stroke | D020521 | EFO_0000712 | I63.9 | 1 | — | — | — | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Muscle spasticity | D009128 | HP_0001257 | — | — | — | — | — | 2 | 2 |
Nausea | D009325 | HP_0002018 | R11.0 | — | — | — | — | 1 | 1 |
Paresis | D010291 | HP_0001269 | — | — | — | — | — | 1 | 1 |
Drug common name | Cyproheptadine |
INN | cyproheptadine |
Description | Cyproheptadine is the product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia. It has a role as a H1-receptor antagonist, a serotonergic antagonist, an antipruritic drug, an anti-allergic agent and a gastrointestinal drug. It is a member of piperidines and a tertiary amine. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 |
PDB | — |
CAS-ID | 129-03-3 |
RxCUI | — |
ChEMBL ID | CHEMBL516 |
ChEBI ID | 4046 |
PubChem CID | 2913 |
DrugBank | DB00434 |
UNII ID | 2YHB6175DO (ChemIDplus, GSRS) |