Brand Name | Status | Last Update |
---|---|---|
amrix | New Drug Application | 2024-04-30 |
cyclo/gaba 10/300 pack | ANDA | 2016-06-22 |
cyclo/mag | unapproved drug other | 2010-03-05 |
cyclo/mag 10mg/200mg | unapproved drug other | 2010-02-17 |
cyclobenzaprine | ANDA | 2024-09-20 |
cyclobenzaprine cyclobenzaprine hydrochloride | ANDA | 2023-04-17 |
cyclobenzaprine hci | ANDA | 2019-04-02 |
cyclobenzaprine hci cyclobenzaprine hcl | ANDA | 2023-06-06 |
cyclobenzaprine hci cyclobenzaprine hcl cyclobenzprine hcl | ANDA | 2019-04-04 |
cyclobenzaprine hcl | NDA authorized generic | 2023-03-31 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 1 | 8 | 2 | 2 | 12 |
Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | 1 | 8 | 2 | 2 | 12 |
Low back pain | D017116 | HP_0003419 | M54.5 | — | — | 3 | 2 | 2 | 7 |
Pain | D010146 | EFO_0003843 | R52 | — | 1 | 1 | 2 | 1 | 5 |
Back pain | D001416 | HP_0003418 | M54 | — | — | 1 | 2 | 1 | 4 |
Spasm | D013035 | — | M62.83 | — | — | 2 | 1 | 1 | 4 |
Postoperative pain | D010149 | — | G89.18 | — | — | — | 2 | 1 | 3 |
Muscle cramp | D009120 | HP_0003394 | — | — | — | 1 | 1 | — | 2 |
Syndrome | D013577 | — | — | — | — | — | 1 | — | 1 |
Somatoform disorders | D013001 | — | F45 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | 4 | 4 | — | — | 8 |
Migraine disorders | D008881 | EFO_0003821 | G43 | — | — | 1 | — | 1 | 2 |
Musculoskeletal pain | D059352 | — | — | — | — | 2 | — | — | 2 |
Muscular diseases | D009135 | HP_0003198 | G72.9 | — | — | 2 | — | — | 2 |
Nervous system diseases | D009422 | — | G00-G99 | — | — | 2 | — | — | 2 |
Rheumatic diseases | D012216 | — | M79.0 | — | — | 2 | — | — | 2 |
Musculoskeletal diseases | D009140 | — | — | — | — | 2 | — | — | 2 |
Neuromuscular diseases | D009468 | EFO_1001902 | G70.9 | — | — | 2 | — | — | 2 |
Collagen diseases | D003095 | — | — | — | — | 2 | — | — | 2 |
Acute pain | D059787 | — | R52 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Disease | D004194 | EFO_0000408 | R69 | — | 2 | — | — | 1 | 3 |
Sprains and strains | D013180 | — | — | — | 1 | — | — | — | 1 |
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | 1 | — | — | — | 1 |
Dyssomnias | D020920 | — | — | — | 1 | — | — | — | 1 |
Parasomnias | D020447 | — | G47.5 | — | 1 | — | — | — | 1 |
Covid-19 | D000086382 | — | — | — | 1 | — | — | — | 1 |
Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
Communicable diseases | D003141 | — | — | — | 1 | — | — | — | 1 |
Post-acute covid-19 syndrome | D000094024 | — | — | — | 1 | — | — | — | 1 |
Stress fractures | D015775 | — | M84.3 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 4 | — | — | — | 1 | 5 |
Depression | D003863 | — | F33.9 | 1 | — | — | — | 1 | 2 |
Sleepiness | D000077260 | — | R40.0 | 1 | — | — | — | — | 1 |
Driving under the influence | D000066448 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Headache | D006261 | HP_0002315 | R51 | — | — | — | — | 1 | 1 |
Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | — | 1 | 1 |
Tendinopathy | D052256 | EFO_1001434 | M77.9 | — | — | — | — | 1 | 1 |
Synovitis | D013585 | EFO_0008997 | M67.5 | — | — | — | — | 1 | 1 |
Radiculopathy | D011843 | — | M54.1 | — | — | — | — | 1 | 1 |
Gout | D006073 | EFO_0004274 | M10 | — | — | — | — | 1 | 1 |
Ankle fractures | D064386 | — | S82.5 | — | — | — | — | 1 | 1 |
Bunion | D000071378 | — | M21.61 | — | — | — | — | 1 | 1 |
Hammer toe syndrome | D037801 | EFO_1001336 | M21.53 | — | — | — | — | 1 | 1 |
Tailor's bunion | D050489 | — | M21.62 | — | — | — | — | 1 | 1 |
Drug common name | Cyclobenzaprine |
INN | cyclobenzaprine |
Description | Cyclobenzaprine is 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm. It has a role as a muscle relaxant, a tranquilizing drug and an antidepressant. It derives from a hydride of a dibenzo[a,d][7]annulene. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN(C)CCC=C1c2ccccc2C=Cc2ccccc21 |
PDB | — |
CAS-ID | 303-53-7 |
RxCUI | — |
ChEMBL ID | CHEMBL669 |
ChEBI ID | 3996 |
PubChem CID | 2895 |
DrugBank | DB00924 |
UNII ID | 69O5WQQ5TI (ChemIDplus, GSRS) |