Custirsen
Custirsen is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Drug
General
| Drug common name | Custirsen |
| INN | custirsen |
| Description | Custirsen, with aliases including custirsen sodium, OGX-011, and CC-8490, is an investigational drug that is under clinical testing for the treatment of cancer. It is an antisense oligonucleotide (ASO) targeting clusterin expression. In metastatic prostate cancer, custirsen showed no benefit in improving overall survival.
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| Classification | Oligonucleotide |
| Drug class | antisense oligonucleotides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 890056-27-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108309 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB05487 |
| UNII ID | L26E95NLRK (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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