Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CORTROSYN | Amphastar Pharmaceuticals | N-016750 RX | 1982-01-01 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
cortrosyn | New Drug Application | 2024-12-01 |
cosyntropin | ANDA | 2024-02-22 |
Code | Description |
---|---|
J0834 | Injection, cosyntropin, 0.25 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Adrenal insufficiency | D000309 | — | — | 1 | — | 1 | 5 | 16 | 23 |
Addison disease | D000224 | — | E27.1 | — | — | — | 1 | 2 | 3 |
Hyperaldosteronism | D006929 | HP_0011736 | E26 | — | — | — | 1 | 2 | 3 |
Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | 1 | — | 2 |
Headache | D006261 | HP_0002315 | R51 | — | 1 | — | 1 | — | 2 |
Post-dural puncture headache | D051299 | — | — | — | 1 | — | 1 | — | 2 |
Hypopituitarism | D007018 | EFO_0001380 | E23.0 | — | — | — | 1 | 1 | 2 |
Arteritis | D001167 | EFO_0009011 | I77.6 | — | — | — | 1 | 1 | 2 |
Giant cell arteritis | D013700 | EFO_1001209 | M31.6 | — | — | — | 1 | 1 | 2 |
Polymyalgia rheumatica | D011111 | EFO_0008518 | M35.3 | — | — | — | 1 | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | 1 | — | 2 | 3 |
Fibrosis | D005355 | — | — | — | — | 1 | — | 2 | 3 |
Spasm | D013035 | — | M62.83 | — | — | 1 | — | — | 1 |
Infantile spasms | D013036 | HP_0011097 | G40.82 | — | — | 1 | — | — | 1 |
Lecithin cholesterol acyltransferase deficiency | D007863 | — | E78.6 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | — | — | 2 | 3 |
Duchenne muscular dystrophy | D020388 | EFO_0000429 | — | — | 1 | — | — | — | 1 |
Muscular dystrophies | D009136 | HP_0003560 | G71.0 | — | 1 | — | — | — | 1 |
Membranous glomerulonephritis | D015433 | EFO_0004254 | N03.2 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 4 | — | — | — | 2 | 6 |
Hyperandrogenism | D017588 | — | — | 4 | — | — | — | 1 | 5 |
Obesity | D009765 | EFO_0001073 | E66.9 | 3 | — | — | — | 1 | 4 |
Overweight | D050177 | — | E66.3 | 2 | — | — | — | — | 2 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | 1 | 2 |
Sleep deprivation | D012892 | — | F51.12 | 2 | — | — | — | — | 2 |
Ketosis | D007662 | HP_0002919 | R82.4 | 1 | — | — | — | — | 1 |
Diabetic ketoacidosis | D016883 | EFO_1000897 | — | 1 | — | — | — | — | 1 |
Hypertension | D006973 | EFO_0000537 | I10 | 1 | — | — | — | — | 1 |
Newborn infant diseases | D007232 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Syndrome | D013577 | — | — | — | — | — | — | 3 | 3 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | — | 2 | 2 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | — | — | 1 | 1 |
Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | — | 1 | 1 |
Adrenal gland neoplasms | D000310 | EFO_0003850 | C74 | — | — | — | — | 1 | 1 |
Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | — | — | — | — | 1 | 1 |
Physiological stress | D013312 | — | — | — | — | — | — | 1 | 1 |
Baroreflex | D017704 | — | — | — | — | — | — | 1 | 1 |
Postural orthostatic tachycardia syndrome | D054972 | — | G90.A | — | — | — | — | 1 | 1 |
Tachycardia | D013610 | HP_0001649 | R00.0 | — | — | — | — | 1 | 1 |
Drug common name | Cosyntropin |
INN | tetracosactide |
Description | Cortrosyn, Cosyntropin (cosyntropin) is a protein pharmaceutical. Cosyntropin was first approved as Cortrosyn on 1982-01-01. The pharmaceutical is active against adrenocorticotropic hormone receptor. |
Classification | Protein |
Drug class | tricyclic compounds; atropine derivatives |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C)C(C)C |
PDB | — |
CAS-ID | 16960-16-0 |
RxCUI | — |
ChEMBL ID | CHEMBL2103784 |
ChEBI ID | 3901 |
PubChem CID | 16132265 |
DrugBank | DB01284 |
UNII ID | 72YY86EA29 (ChemIDplus, GSRS) |