Cosyntropin
Cortrosyn, Cosyntropin (cosyntropin) is a protein pharmaceutical. Cosyntropin was first approved as Cortrosyn on 1982-01-01. The pharmaceutical is active against adrenocorticotropic hormone receptor.
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Drug
Target
Variants
Financial
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YTD
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Completion date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Cortrosyn, Cosyntropin (discontinued: Cosyntropin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cosyntropin
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CORTROSYN | Amphastar Pharmaceuticals | N-016750 RX | 1982-01-01 | 1 products, RLD, RS |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cortrosyn | New Drug Application | 2024-12-01 |
| cosyntropin | ANDA | 2024-02-22 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J0834 | Injection, cosyntropin, 0.25 mg |
Clinical
No data
Drug
General
| Drug common name | Cosyntropin |
| INN | tetracosactide |
| Description | Cortrosyn, Cosyntropin (cosyntropin) is a protein pharmaceutical. Cosyntropin was first approved as Cortrosyn on 1982-01-01. The pharmaceutical is active against adrenocorticotropic hormone receptor. |
| Classification | Protein |
| Drug class | tricyclic compounds; atropine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O)C(C)C)C(C)C)C(C)C |
Identifiers
| PDB | — |
| CAS-ID | 16960-16-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2103784 |
| ChEBI ID | 3901 |
| PubChem CID | 16132265 |
| DrugBank | DB01284 |
| UNII ID | 72YY86EA29 (ChemIDplus, GSRS) |
Target
Agency Approved
MC2R
MC2R
Organism
Homo sapiens
Gene name
MC2R
Gene synonyms
ACTHR
NCBI Gene ID
Protein name
adrenocorticotropic hormone receptor
Protein synonyms
ACTH receptor, Adrenocorticotropin receptor, corticotropin receptor, MC2 receptor, MC2-R, melanocortin 2 receptor (adrenocorticotropic hormone), Melanocortin receptor 2
Uniprot ID
Mouse ortholog
Mc2r (17200)
adrenocorticotropic hormone receptor (Q64326)
Alternate
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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