Corticorelin
Corticorelin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| acthrel | Biologic Licensing Application | 2021-11-12 |
Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
Code | Description |
|---|---|
| J0795 | Injection, corticorelin ovine triflutate, 1 microgram |
Clinical
Clinical Trials
1787 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 4 | 4 | 3 | 5 | 1 | 17 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 3 | 3 | 4 | 3 | 1 | 14 |
| Hyperparathyroidism | D006961 | EFO_0008506 | E21.3 | 1 | 2 | 3 | 2 | 1 | 9 |
| Secondary hyperparathyroidism | D006962 | EFO_1001173 | — | 1 | 2 | 2 | 2 | 1 | 8 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | 1 | 2 | 1 | 4 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | 3 | 1 | 4 |
| Renal insufficiency | D051437 | — | N19 | 2 | — | — | 1 | — | 3 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | 1 | — | 1 |
| Vascular calcification | D061205 | — | — | — | — | — | 1 | — | 1 |
| Calcinosis | D002114 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 1 | 2 | — | 1 | 4 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 1 | — | — | — | — | 1 |
| Dyslipidemias | D050171 | — | — | 1 | — | — | — | — | 1 |
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Corticorelin |
| INN | corticorelin |
| Description | Corticorelin (INN, trade name Xerecept) is a diagnostic agent. It is a synthetic form of human corticotropin-releasing hormone (hCRH).
|
| Classification | Protein |
| Drug class | prehormones or hormone-release stimulating peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108182 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB09067 |
| UNII ID | 56X54T817Q (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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11 adverse events reported
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