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Drug ReportsColfosceril
Colfosceril palmitate
Exosurf Neonatal (colfosceril palmitate) is a small molecule pharmaceutical. Colfosceril palmitate was first approved as Exosurf neonatal on 1990-08-02. It is used to treat newborn respiratory distress syndrome in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
hereditary congenital and neonatal diseases and abnormalitiesD009358
Trade Name
FDA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cetyl alcohol
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Colfosceril palmitate
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Tyloxapol
Tradename
Company
Number
Date
Products
EXOSURF NEONATALGSKN-020044 DISCN1990-08-02
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
newborn respiratory distress syndrome—D012127P22
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
— R07: Other respiratory system products in atc
— R07A: Other respiratory system products in atc
— R07AA: Lung surfactants
— R07AA01: Colfosceril palmitate
HCPCS
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Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Respiratory distress syndromeD012128EFO_1000637J80—11——1
Premature birthD047928EFO_0003917O60—11——1
Bronchopulmonary dysplasiaD001997—P27.8—11——1
Birth weightD001724EFO_0004344——11——1
Newborn respiratory distress syndromeD012127—P22—11——1
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameColfosceril palmitate
INNcolfosceril palmitate
Description
Colfosceril palmitate (trade name Exosurf) is a drug used as a pulmonary surfactant. It is a drug that is used in surfactant deficient conditions such as infant respiratory distress syndrome in newborns.
Classification
Small molecule
Drug classphosphoro-derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC
Identifiers
PDB—
CAS-ID2644-64-6
RxCUI—
ChEMBL IDCHEMBL1200737
ChEBI ID72999
PubChem CID6138
DrugBank—
UNII ID319X2NFW0A (ChemIDplus, GSRS)
Target
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Trends
PubMed Central
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Safety
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No Black-box warning
Adverse Events
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6 adverse events reported
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