PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsClidinium
Clidinium
Chlordiazepoxide / Clidinium, Librax, Quarzan (clidinium) is a small molecule pharmaceutical. Clidinium was first approved as Librax on 1982-01-01. It is used to treat inflammatory bowel diseases and peptic ulcer in the USA. The pharmaceutical is active against muscarinic acetylcholine receptor M3. In addition, it is known to target muscarinic acetylcholine receptor M2.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
Trade Name
FDA
EMA
Combinations
Chlordiazepoxide clidinium, Librax (discontinued: Chlordiazepoxide clidinium)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Clidinium bromide
Tradename
Company
Number
Date
Products
QUARZANRocheN-010355 DISCN1982-01-01
2 products
Hide discontinued
Chlordiazepoxide hydrochloride
+
Clidinium bromide
Tradename
Company
Number
Date
Products
LIBRAXBausch Health CompaniesN-012750 RX1982-01-01
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
chlordiazepoxide hcl and clidinium bromideANDA2023-04-26
chlordiazepoxide hydrochloride and clidinium bromideANDA2024-10-09
chlordiazepoxide hydrochloride/clidinium bromideunapproved drug other2019-04-01
libraxNew Drug Application2023-01-13
not applicableANDA2021-12-27
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
peptic ulcerHP_0004398D010437K27
inflammatory bowel diseasesEFO_0003767D015212—
alcohol withdrawal deliriumEFO_1000800D000430—
anxiety disordersEFO_0006788D001008F41.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A03: Drugs for functional gastrointestinal disorders
— A03C: Antispasmodics in combination with psycholeptics
— A03CA: Synthetic anticholinergic agents in combination with psycholeptics
— A03CA02: Clidinium and psycholeptics
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chest painD002637HP_0100749R07.9————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameClidinium
INNclidinium bromide
Description
Clidinium is the ester resulting from formal condensation of benzilic acid and 3-hydroxy-1-methyl-1-azoniabicyclo[2.2.2]octane. It is used, generally as the bromide, for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome. It has a role as a parasympatholytic, an antispasmodic drug and an anti-arrhythmia drug. It is a quaternary ammonium ion, a carboxylic ester and an organic cation. It is functionally related to a benzilic acid and a 3-quinuclidinol.
Classification
Small molecule
Drug classquaternary ammonium derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C[N+]12CCC(CC1)C(OC(=O)C(O)(c1ccccc1)c1ccccc1)C2
Identifiers
PDB—
CAS-ID7020-55-5
RxCUI—
ChEMBL IDCHEMBL620
ChEBI ID—
PubChem CID2784
DrugBankDB00771
UNII IDBO76JF850N (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Clidinium
+
Chlordiazepoxide
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Clidinium
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 172 documents
View more details
Safety
Black-box Warning
Black-box warning for: Chlordiazepoxide hcl and clidinium bromide, Chlordiazepoxide hydrochloride and clidinium bromide, Chlordiazepoxide hydrochloride/clidinium bromide, Librax, Not applicable
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
42,656 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use