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Drug ReportsCiticoline
Citicoline
Citicoline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
No data
Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N06: Psychoanaleptics
N06B: Psychostimulants, agents used for adhd and nootropics
N06BX: Other psychostimulants and nootropics in atc
N06BX06: Citicoline
HCPCS
No data
Clinical
Clinical Trials
69 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GlaucomaD005901EFO_0000516H40121812
Cerebral infarctionD002544I633126
IschemiaD007511EFO_000055612126
Traumatic brain injuriesD000070642S0621115
Brain injuriesD001930S06.92114
Optic nerve diseasesD009901EFO_1001330H47.14224
Bipolar disorderD001714EFO_0000289F30.9213
Ischemic optic neuropathyD018917EFO_1000809H47.01213
AlcoholismD000437EFO_0003829F10.1123
Cocaine-related disordersD019970F14112
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ischemic strokeD00008324221417
Open-angle glaucomaD005902EFO_0004190H40.11157
StrokeD020521EFO_0000712I63.911416
InfarctionD007238EFO_0009463112
HypoxiaD000860R09.02112
Brain hypoxia-ischemiaD020925EFO_1000846P91.6112
ManiaD000087122F3011
CarcinomaD002277C80.011
Urinary bladder neoplasmsD001749C6711
Transitional cell carcinomaD00229511
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Indications Phases 2
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Retinal diseasesD012164H35.9112
Diabetic retinopathyD003930EFO_0003770112
Brain diseasesD001927G93.4011
Brain ischemiaD002545EFO_0003883I67.8211
Indications Without Phase
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCiticoline
INNciticoline
Description
CDP-choline is a member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes. It has a role as a human metabolite, a psychotropic drug, a neuroprotective agent, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a member of phosphocholines and a member of nucleotide-(amino alcohol)s. It is functionally related to a CDP. It is a conjugate base of a CDP-choline(1+).
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O
Identifiers
PDB
CAS-ID987-78-0
RxCUI997602
ChEMBL IDCHEMBL1618340
ChEBI ID49086
PubChem CID13804
DrugBankDB12153
UNII ID536BQ2JVC7 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,116 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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153 adverse events reported
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