Brand Name | Status | Last Update |
---|---|---|
cisatracurium | ANDA | 2025-02-21 |
cisatracurium besylate | ANDA | 2025-05-15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neuromuscular blockade | D019148 | — | — | — | — | — | 1 | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
General anesthesia | D000768 | — | — | — | — | 1 | — | — | 1 |
Drug common name | Cisatracurium |
INN | cisatracurium besilate |
Description | Cisatracurium besylate is the (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. Cisatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia. It has a role as a muscle relaxant and a nicotinic antagonist. It is a quaternary ammonium salt, an atracurium besylate and an organosulfonate salt. It contains a cisatracurium. |
Classification | Small molecule |
Drug class | quaternary ammonium derivatives: neuromuscular blocking agents |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COc1ccc(C[C@@H]2c3cc(OC)c(OC)cc3CC[N@+]2(C)CCC(=O)OCCCCCOC(=O)CC[N@@+]2(C)CCc3cc(OC)c(OC)cc3[C@H]2Cc2ccc(OC)c(OC)c2)cc1OC |
PDB | — |
CAS-ID | 96946-41-7 |
RxCUI | — |
ChEMBL ID | CHEMBL1201248 |
ChEBI ID | — |
PubChem CID | 62886 |
DrugBank | DB00565 |
UNII ID | 80YS8O1MBS (ChemIDplus, GSRS) |