Brand Name | Status | Last Update |
---|---|---|
cinacalcet | ANDA | 2025-01-29 |
cinacalcet hydrochloride | ANDA | 2024-05-24 |
sensipar | New Drug Application | 2024-10-31 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
parathyroid neoplasms | — | D010282 | — |
secondary hyperparathyroidism | EFO_1001173 | D006962 | — |
primary hyperparathyroidism | EFO_0008519 | D049950 | E21.0 |
Code | Description |
---|---|
J0604 | Cinacalcet, oral, 1 mg, (for esrd on dialysis) |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hyperparathyroidism | D006961 | EFO_0008506 | E21.3 | 1 | 8 | 14 | 7 | 4 | 34 |
Secondary hyperparathyroidism | D006962 | EFO_1001173 | — | 1 | 4 | 11 | 6 | 3 | 25 |
Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 4 | 10 | 5 | 1 | 21 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 3 | 9 | 4 | 1 | 18 |
Chronic renal insufficiency | D051436 | — | N18 | 1 | 2 | 8 | 4 | 1 | 16 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 4 | 4 | 3 | 1 | 12 |
Primary hyperparathyroidism | D049950 | EFO_0008519 | E21.0 | — | 4 | 1 | 1 | 1 | 7 |
Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | 1 | 1 | 2 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | 1 | — | 1 |
Vascular calcification | D061205 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Kidney transplantation | D016030 | — | — | — | — | 1 | — | 2 | 3 |
Hypercalcemia | D006934 | HP_0003072 | E83.52 | — | — | 1 | — | — | 1 |
Hypophosphatemia | D017674 | HP_0002148 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic kidney disease-mineral and bone disorder | D012080 | EFO_1001152 | N25.0 | — | 1 | — | — | — | 1 |
Renal insufficiency | D051437 | — | N19 | — | 1 | — | — | — | 1 |
Drug common name | Cinacalcet |
INN | cinacalcet |
Description | Cinacalcet is a secondary amino compound that is (1R)-1-(naphthalen-1-yl)ethanamine in which one of the hydrogens attached to the nitrogen is substituted by a 3-[3-(trifluoromethyl)phenyl]propyl group. It has a role as a calcimimetic and a P450 inhibitor. It is a member of naphthalenes, a secondary amino compound and a member of (trifluoromethyl)benzenes. |
Classification | Small molecule |
Drug class | calcium-sensing receptor (CaSR) agonists |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 |
PDB | — |
CAS-ID | 226256-56-0 |
RxCUI | — |
ChEMBL ID | CHEMBL1201284 |
ChEBI ID | 48390 |
PubChem CID | 156419 |
DrugBank | DB01012 |
UNII ID | UAZ6V7728S (ChemIDplus, GSRS) |