Cilengitide
Cilengitide is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
30 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | 4 | 9 | 1 | — | — | 13 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Recurrence | D012008 | — | — | 4 | 5 | — | — | — | 8 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 4 | 2 | — | — | — | 6 |
| Gliosarcoma | D018316 | — | — | 3 | 2 | — | — | — | 4 |
| Glioma | D005910 | EFO_0000520 | — | 2 | 2 | — | — | — | 4 |
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | 2 | — | — | — | 3 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 1 | — | — | — | 2 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 1 | 1 | — | — | — | 2 |
| Central nervous system neoplasms | D016543 | — | — | 2 | 1 | — | — | — | 2 |
| Nervous system neoplasms | D009423 | — | — | 2 | 1 | — | — | — | 2 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | 1 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 5 | — | — | — | — | 5 |
| Lymphoma | D008223 | — | C85.9 | 2 | — | — | — | — | 2 |
| Syndrome | D013577 | — | — | 2 | — | — | — | — | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Triple negative breast neoplasms | D064726 | — | — | 1 | — | — | — | — | 1 |
| Male breast neoplasms | D018567 | — | — | 1 | — | — | — | — | 1 |
| Small cell lung carcinoma | D055752 | — | — | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
| Mycoses | D009181 | — | B35-B49 | 1 | — | — | — | — | 1 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cilengitide |
| INN | cilengitide |
| Description | Cilengitide is an oligopeptide. |
| Classification | Protein |
| Drug class | peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](Cc2ccccc2)C(=O)N1C |
Identifiers
| PDB | — |
| CAS-ID | 188968-51-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL429876 |
| ChEBI ID | — |
| PubChem CID | 176873 |
| DrugBank | DB11890 |
| UNII ID | 4EDF46E4GI (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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246 adverse events reported
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