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AboutPricing
Drug ReportsCetirizine
Cetirizine
Cetirizine, Quzyttir, Zerviate, Zyrtec (cetirizine) is a small molecule pharmaceutical. Cetirizine was first approved as Zyrtec on 1996-09-27. It is used to treat allergic rhinitis perennial and urticaria in the USA. The pharmaceutical is active against histamine H1 receptor.
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YTD
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
skin and connective tissue diseasesD017437
immune system diseasesD007154
Trade Name
FDA
EMA
Cetirizine, Quzyttir, Zerviate, Zyrtec (discontinued: Cetirizine, Zyrtec)
Combinations
Cetirizine pseudoephedrine, Zyrtec (discontinued: Cetirizine pseudoephedrine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cetirizine hydrochloride
Tradename
Company
Number
Date
Products
CETIRIZINE HYDROCHLORIDE ALLERGYBionPharmaN-022429 OTC2009-07-23
1 products, RLD
CETIRIZINE HYDROCHLORIDE HIVES RELIEFBionPharmaN-022429 OTC2009-07-23
2 products, RLD
CETIRIZINE HYDROCHLORIDE ALLERGYBionPharmaN-022429 OTC2009-07-23
1 products, RLD, RS
ZERVIATEHarrowN-208694 RX2017-05-30
1 products, RLD, RS
CHILDREN'S ZYRTEC HIVES RELIEFJohnson & JohnsonN-022155 OTC2007-11-16
1 products, RLD, RS
CHILDREN'S ZYRTEC ALLERGYJohnson & JohnsonN-022155 OTC2007-11-16
1 products, RLD, RS
CHILDREN'S ZYRTEC ALLERGYJohnson & JohnsonN-021621 OTC2007-11-16
2 products, RLD
ZYRTEC ALLERGYJohnson & JohnsonN-022578 OTC2010-09-03
1 products, RLD, RS
ZYRTEC ALLERGYJohnson & JohnsonN-019835 OTC2007-11-16
1 products, RLD, RS
QUZYTTIRJDP TherapeuticsN-211415 RX2019-10-04
1 products, RLD, RS
Show 5 discontinued
Cetirizine hydrochloride
+
Pseudoephedrine hydrochloride
Tradename
Company
Number
Date
Products
ZYRTEC-D 12 HOURJohnson & JohnsonN-021150 OTC2007-11-09
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
12 hour allergy dANDA2020-09-03
24 hour allergyNew Drug Application2024-04-01
all dayANDA2020-06-18
all day allergyANDA2025-04-07
all day allergy dANDA2025-02-12
all day allergy reliefANDA2024-12-20
all day allergy relief dANDA2018-12-06
allergyANDA2024-06-03
allergy and congestion relief dANDA2023-05-30
allergy reliefANDA2025-03-13
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
allergic rhinitis perennialEFO_1001417D012221J30.89
urticariaEFO_0005531D014581L50
sinusitisEFO_0007486D012852J32
asthmaEFO_0000270D001249J45
common coldEFO_0007214D003139J00
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Cetirizine Hydrochloride, Zerviate, Eyevance
92542862032-07-09DP
88290052030-03-15U-1680
97506842030-03-15DP
99934712030-03-15U-1680
Cetirizine Hydrochloride, Quzyttir, Jdp
82635812030-02-28U-2635
83140832030-02-28U-2634
85132592030-02-11U-2636
91197712030-02-11U-2635
91800902030-02-11U-2635
ATC Codes
R: Respiratory system drugs
— R06: Antihistamines for systemic use
— R06A: Antihistamines for systemic use
— R06AE: Piperazine derivatives, systemic antihistamines
— R06AE07: Cetirizine
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01G: Decongestants and antiallergics
— S01GX: Other antiallergics in atc
— S01GX12: Cetirizine
HCPCS
Code
Description
J1201
Injection, cetirizine hydrochloride, 0.5 mg
Clinical
Clinical Trials
146 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DiseaseD004194EFO_0000408R69————22
Healthy volunteers/patients———————22
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCetirizine
INNcetirizine
Description
Cetirizine is a member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively. It has a role as an anti-allergic agent, a H1-receptor antagonist, an environmental contaminant and a xenobiotic. It is a monocarboxylic acid, a member of piperazines, a member of monochlorobenzenes and an ether.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1
Identifiers
PDB—
CAS-ID83881-51-0
RxCUI—
ChEMBL IDCHEMBL1000
ChEBI ID3561
PubChem CID2678
DrugBankDB00341
UNII IDYO7261ME24 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
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Estimated US medical usage
Cetirizine
Total medical expenditures per year (USD, in millions)
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Cetirizine
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Pseudoephedrine
Total medical expenditures per year (USD, in millions)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 5,139 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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58,546 adverse events reported
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