Cendakimab
Cendakimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Eosinophilic esophagitis | D057765 | EFO_0004232 | K20.0 | 1 | 1 | 2 | — | — | 4 |
| Esophagitis | D004941 | HP_0100633 | K20 | 1 | 1 | 2 | — | — | 4 |
| Gastrointestinal diseases | D005767 | — | — | — | — | 2 | — | — | 2 |
| Gastroenteritis | D005759 | EFO_1001463 | K52.9 | — | — | 2 | — | — | 2 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | 1 | — | — | 1 |
| Eosinophilia | D004802 | — | D72.1 | — | — | 1 | — | — | 1 |
| Esophageal diseases | D004935 | EFO_0009544 | K22.9 | — | — | 1 | — | — | 1 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | — | — | 1 | 2 |
| Eczema | D004485 | — | L30.9 | — | 1 | — | — | 1 | 2 |
| Dermatitis | D003872 | — | L30.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 4 | — | — | — | — | 4 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Psoriasis | D011565 | EFO_0000676 | L40 | — | — | — | — | 1 | 1 |
| Neoplasms | D009369 | — | C80 | — | — | — | — | 1 | 1 |
| Hidradenitis suppurativa | D017497 | — | L73.2 | — | — | — | — | 1 | 1 |
| Pruritus | D011537 | — | L29 | — | — | — | — | 1 | 1 |
| Mycosis fungoides | D009182 | — | C84.0 | — | — | — | — | 1 | 1 |
| T-cell lymphoma cutaneous | D016410 | — | C84.A | — | — | — | — | 1 | 1 |
| Abscess | D000038 | EFO_0003030 | — | — | — | — | — | 1 | 1 |
| Chronic urticaria | D000080223 | — | L50.8 | — | — | — | — | 1 | 1 |
| Exanthema | D005076 | — | — | — | — | — | — | 1 | 1 |
| Urticaria | D014581 | EFO_0005531 | L50 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cendakimab |
| INN | cendakimab |
| Description | Cendakimab (RPC4046; ABT 308; CC-93538) is a monoclonal antibody against interleukin 13. It is developed by Bristol Myers Squibb for eosinophilic esophagitis.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297864 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB18427 |
| UNII ID | O8R9U9ZUVN (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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