Brand Name | Status | Last Update |
---|---|---|
libtayo | Biologic Licensing Application | 2024-06-05 |
Code | Description |
---|---|
J9119 | Injection, cemiplimab-rwlc, 1 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Carcinoma | D002277 | — | C80.0 | 8 | 15 | 4 | — | 2 | 27 |
Squamous cell carcinoma | D002294 | — | — | 7 | 15 | 2 | — | 3 | 26 |
Non-small-cell lung carcinoma | D002289 | — | — | 5 | 18 | 6 | — | 2 | 24 |
Lung neoplasms | D008175 | — | C34.90 | 3 | 10 | 6 | — | 2 | 17 |
Melanoma | D008545 | — | — | 3 | 9 | 4 | — | — | 13 |
Squamous cell neoplasms | D018307 | — | — | 2 | 1 | 1 | — | — | 4 |
Uterine cervical neoplasms | D002583 | — | — | 1 | 2 | 1 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 12 | 8 | — | — | — | 15 |
Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | 9 | — | — | — | 12 |
Prostatic neoplasms | D011471 | — | C61 | 6 | 5 | — | — | — | 7 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 5 | 5 | — | — | — | 6 |
Basal cell carcinoma | D002280 | — | — | 1 | 2 | — | — | 1 | 4 |
Basal cell neoplasms | D018295 | — | — | 1 | 2 | — | — | 1 | 4 |
Recurrence | D012008 | — | — | 3 | 2 | — | — | — | 4 |
Head and neck neoplasms | D006258 | — | — | 3 | 2 | — | — | — | 3 |
Fallopian tube neoplasms | D005185 | — | — | 3 | 2 | — | — | — | 3 |
Colorectal neoplasms | D015179 | — | — | 1 | 3 | — | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
Anaplastic thyroid carcinoma | D065646 | — | — | 1 | — | — | — | — | 1 |
Thyroid diseases | D013959 | — | E00-E07 | 1 | — | — | — | — | 1 |
Drug common name | Cemiplimab |
INN | cemiplimab |
Description | Cemiplimab, sold under the brand name Libtayo, is a monoclonal antibody medication for the treatment of squamous cell skin cancer. Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway.
|
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | >8GY5:A,H|heavy chain
EVQLLESGGVLVQPGGSLRLSCAASGFTFSNFGMTWVRQAPGKGLEWVSGISGGGRDTYFADSVKGRFTISRDNSKNTLY
LQMNSLKGEDTAVYYCVKWGNIYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHHHHHH
>8GY5:B,L|light chain
DIQMTQSPSSLSASVGDSITITCRASLSINTFLNWYQQKPGKAPNLLIYAASSLHGGVPSRFSGSGSGTDFTLTIRTLQP
EDFATYYCQQSSNTPFTFGPGTVVDFRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
PDB | 7WVM, 8GY5 |
CAS-ID | — |
RxCUI | 2058826 |
ChEMBL ID | CHEMBL4297723 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB14707 |
UNII ID | 6QVL057INT (ChemIDplus, GSRS) |