Cemdisiran
Cemdisiran is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
14 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Paroxysmal hemoglobinuria | D006457 | Orphanet_447 | D59.12 | — | 2 | 3 | — | 1 | 6 |
| Hemoglobinuria | D006456 | — | R82.3 | — | 2 | 3 | — | 1 | 6 |
| Myasthenia gravis | D009157 | EFO_0004991 | G70.0 | — | — | 1 | — | — | 1 |
| Muscle weakness | D018908 | HP_0001324 | — | — | — | 1 | — | — | 1 |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | — | 1 | — | — | 1 |
| Geographic atrophy | D057092 | — | — | — | — | 1 | — | — | 1 |
| Atrophy | D001284 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemolytic-uremic syndrome | D006463 | — | D59.3 | — | 2 | — | — | — | 2 |
| Atypical hemolytic uremic syndrome | D065766 | — | — | — | 2 | — | — | — | 2 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | — | — | — | 1 |
| Glomerulonephritis | D005921 | HP_0000099 | N05 | — | 1 | — | — | — | 1 |
| Iga glomerulonephritis | D005922 | EFO_0004194 | — | — | 1 | — | — | — | 1 |
| Hemolysis | D006461 | — | — | — | 1 | — | — | — | 1 |
| Syndrome | D013577 | — | — | — | 1 | — | — | — | 1 |
| Azotemia | D053099 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Myositis | D009220 | EFO_0000783 | G72.49 | 1 | — | — | — | — | 1 |
| Inclusion body myositis | D018979 | EFO_0007323 | G72.41 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cemdisiran |
| INN | cemdisiran |
| Description | Cemdisiran is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Oligonucleotide |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1436858-07-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297722 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | S66Z65E10T (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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