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AboutPricing
Drug ReportsCeftriaxone
Ceftriaxone
Ceftriaxone, Rocephin (ceftriaxone) is a small molecule pharmaceutical. Ceftriaxone was first approved as Rocephin on 1984-12-21. It is used to treat acinetobacter infections, bacterial infections, bacterial meningitis, bacterial pneumonia, and bacterial skin diseases amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
digestive system diseasesD004066
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
nervous system diseasesD009422
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Ceftriaxone (discontinued: Ceftriaxone, Rocephin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ceftriaxone sodium
Tradename
Company
Number
Date
Products
CEFTRIAXONE AND DEXTROSE IN DUPLEX CONTAINERB. Braun MedicalN-050796 RX2005-04-20
2 products, RLD, RS
Show 2 discontinued
Ceftriaxone sodium
+
Lidocaine
Tradename
Company
Number
Date
Products
ROCEPHIN KITRocheN-050585 DISCN1996-05-08
2 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
ceftriaxoneANDA2024-10-07
ceftriaxone and dextroseNew Drug Application2022-01-13
ceftriaxone ceftriaxoneANDA2019-08-14
ceftriaxone sodiumANDA2024-08-20
easy-ceftANDA2021-01-07
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
sepsisHP_0100806D018805A41.9
urinary tract infectionsEFO_0003103D014552N39.0
otitis mediaEFO_0004992D010033H66.9
bacterial infections—D001424A49
gonorrheaDOID_7551D006069A54
pseudomonas infectionsEFO_0001076D011552A41.52
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
pelvic infection—D034161—
soft tissue infections—D018461—
Show 27 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DD: Third-generation cephalosporins
— J01DD04: Ceftriaxone
— J01DD54: Ceftriaxone, combinations
— J01DD63: Ceftriaxone and beta-lactamase inhibitor
HCPCS
Code
Description
J0696
Injection, ceftriaxone sodium, per 250 mg
Clinical
Clinical Trials
249 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PneumoniaD011014EFO_0003106——1—1—2
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial pneumoniaD018410EFO_1001272J15.9—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20————11
Hiv seropositivityD006679——————11
NeurosyphilisD009494EFO_0007339A50.4————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCeftriaxone
INNceftriaxone
Description
Ceftriaxone is a third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups. It has a role as an antibacterial drug, an EC 3.5.2.6 (beta-lactamase) inhibitor and a drug allergen. It is a cephalosporin, a member of 1,2,4-triazines, a member of 1,3-thiazoles and an oxime O-ether. It is a conjugate acid of a ceftriaxone(1-).
Classification
Small molecule
Drug classcephalosporins
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Structure (InChI/SMILES or Protein Sequence)
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nc(=O)c(O)nn3C)CS[C@H]12)c1csc(N)n1
Identifiers
PDB—
CAS-ID73384-59-5
RxCUI—
ChEMBL IDCHEMBL161
ChEBI ID29007
PubChem CID5479530
DrugBankDB01212
UNII ID75J73V1629 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Rocephin – Roche
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Estimated US medical usage
Ceftriaxone
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 58,253 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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21,744 adverse events reported
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