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Drug ReportsCeftazidime
Fortaz, Zavicefta(ceftazidime)
Avycaz, Ceftazidime, Fortaz, Tazicef, Zavicefta (ceftazidime) is a small molecule pharmaceutical. Ceftazidime was first approved as Fortaz on 1985-07-19. It is used to treat acinetobacter infections, bacterial infections, bacterial meningitis, bacterial pneumonia, and bacterial skin diseases amongst others in the USA. It has been approved in Europe to treat bacterial pneumonia, gram-negative bacterial infections, pneumonia, soft tissue infections, and urinary tract infections.
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Drug
Target
Variants
Financial
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Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
hemic and lymphatic diseasesD006425
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Tazicef (discontinued: Ceftazidime, Ceptaz, Fortaz, Pentacef, Tazicef, Tazidime)
Combinations
Avycaz
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ceftazidime
Tradename
Company
Number
Date
Products
CEFTAZIDIME IN DEXTROSE CONTAINERB. Braun MedicalN-050823 DISCN2011-06-13
2 products, RLD
CEPTAZGSKN-050646 DISCN1990-09-27
4 products
FORTAZPAI PharmaN-050578 DISCN1985-07-19
4 products, RLD
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Avibactam sodium
+
Ceftazidime
Tradename
Company
Number
Date
Products
AVYCAZAbbVieN-206494 RX2015-02-25
1 products, RLD, RS
Ceftazidime sodium
Tradename
Company
Number
Date
Products
FORTAZ IN PLASTIC CONTAINERPAI PharmaN-050634 DISCN1989-04-28
3 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
avycazNew Drug Application2025-04-25
ceftazidimeANDA2024-01-03
fortametNew Drug Application2010-03-15
fortazNew Drug Application2017-07-28
tazicefANDA2024-07-04
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
sepsisEFO_0001420D018805A41.9
neutropenia—D009503D70
fever—D005334R50.9
urinary tract infectionsEFO_0003103D014552N39.0
bacterial infections—D001424A49
pseudomonas infectionsEFO_0001076D011552A41.52
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
soft tissue infections—D018461—
streptococcal infectionsEFO_1001476D013290—
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Agency Specific
FDA
EMA
Expiration
Code
AVIBACTAM SODIUM / CEFTAZIDIME, AVYCAZ, ALLERGAN
2025-12-20NPP
2025-02-25GAIN
2020-02-25NCE
Patent Expiration
Patent
Expires
Flag
FDA Information
Avibactam Sodium / Ceftazidime, Avycaz, Allergan
89695662032-06-15DP
92843142032-06-15DP
96951222032-06-15DP
84710252031-08-12DP
88354552030-10-08DP
76120872026-11-12DP
71125922026-01-07DS, DPU-282, U-2244, U-2508, U-3818
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DD: Third-generation cephalosporins
— J01DD02: Ceftazidime
— J01DD52: Ceftazidime and beta-lactamase inhibitor
HCPCS
Code
Description
J0713
Injection, ceftazidime, per 500 mg
J0714
Injection, ceftazidime and avibactam, 0.5 g/0.125 g
Clinical
Clinical Trials
136 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
FibrosisD005355—————1—1
Cystic fibrosisD003550EFO_0000390E84———1—1
Pseudomonas aeruginosaD011550NCBITaxon_287————1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial infectionsD001424—A49————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCeftazidime
INNceftazidime
Description
Ceftazidime is a third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a role as an antibacterial drug, an EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor and a drug allergen. It is a cephalosporin and an oxime O-ether. It is a conjugate acid of a ceftazidime(1-).
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)O
Identifiers
PDB—
CAS-ID72558-82-8
RxCUI—
ChEMBL IDCHEMBL44354
ChEBI ID3508
PubChem CID5481173
DrugBankDB00438
UNII IDDZR1ENT301 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
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Zavicefta – Pfizer
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Avycaz – Allergan
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Avycaz – Warner Chilcott
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Estimated US medical usage
Ceftazidime
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 39,950 documents
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Safety
Black-box Warning
Black-box warning for: Fortamet
Adverse Events
Top Adverse Reactions
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10,020 adverse events reported
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