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Drug ReportsCefotiam
Cefotiam
Ceradon (cefotiam) is a small molecule pharmaceutical. Cefotiam was first approved as Ceradon on 1988-12-30. It is used to treat bacterial infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefotiam hydrochloride
Tradename
Company
Number
Date
Products
CERADONTakedaN-050601 DISCN1988-12-30
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DC: Second-generation cephalosporins
— J01DC07: Cefotiam
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver cirrhosisD008103EFO_0001422K74.0————22
Esophageal and gastric varicesD004932EFO_0009545I85————22
Varicose veinsD014648HP_0002619I83.90————22
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCefotiam
INNcefotiam
Description
Cefotiam is a cephalosporin with ({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl and (2-amino-1,3-thiazol-4-yl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. A third generation beta-lactam cephalosporin antibiotic, it is active against a broad spectrum of both Gram positive and Gram negative bacteria. It has a role as an antibacterial drug. It is a cephalosporin, a semisynthetic derivative and a beta-lactam antibiotic allergen.
Classification
Small molecule
Drug classcephalosporins
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Structure (InChI/SMILES or Protein Sequence)
CN(C)CCn1nnnc1SCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3csc(N)n3)[C@H]2SC1
Identifiers
PDB—
CAS-ID61622-34-2
RxCUI—
ChEMBL IDCHEMBL1296
ChEBI ID355510
PubChem CID43708
DrugBankDB00229
UNII ID91W6Z2N718 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 972 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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187 adverse events reported
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