Cefotetan
Cefotan, Cefotetan (cefotetan) is a small molecule pharmaceutical. Cefotetan was first approved as Cefotan on 1985-12-27. It is used to treat abscess, bacterial infections, bacterial skin diseases, bacteroides infections, and clostridium infections amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Cefotan (generic drugs available since 2007-08-09)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefotetan disodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CEFOTAN | PAI Pharma | N-050588 RX | 1985-12-27 | 2 products, RLD |
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
Code | Description |
|---|---|
| S0074 | Injection, cefotetan disodium, 500 mg |
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Surgical wound infection | D013530 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
| Cholecystitis | D002764 | HP_0001082 | K81 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pregnancy complications | D011248 | — | — | — | — | — | — | 1 | 1 |
| Infectious pregnancy complications | D011251 | — | — | — | — | — | — | 1 | 1 |
| Rotator cuff injuries | D000070636 | — | M75.1 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cefotetan |
| INN | cefotetan |
| Description | Cefotetan is a semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms. It has a role as an antibacterial drug. It is a conjugate acid of a cefotetan(2-). |
| Classification | Small molecule |
| Drug class | cephalosporins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CO[C@@]1(NC(=O)C2SC(=C(C(N)=O)C(=O)O)S2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@@H]21 |
Identifiers
| PDB | — |
| CAS-ID | 69712-56-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL474579 |
| ChEBI ID | 3499 |
| PubChem CID | 53025 |
| DrugBank | DB01330 |
| UNII ID | 48SPP0PA9Q (ChemIDplus, GSRS) |
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Estimated US medical usage
Cefotetan
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Trends
PubMed Central
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Additional graphs summarizing 1,848 documents
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Safety
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Adverse Events
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81 adverse events reported
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