Cefdinir
Cefdinir (cefdinir) is a small molecule pharmaceutical. Cefdinir was first approved as Omnicef on 1997-12-04. It is used to treat bacterial infections, bacterial pneumonia, bacterial skin diseases, bronchitis, and escherichia coli infections amongst others in the USA.
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Commercial
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Cefdinir (discontinued: Omnicef)
Drug Products
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cefdinir | ANDA | 2024-12-07 |
Indications
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Agency Specific
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Clinical
Clinical Trials
32 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 9 | — | — | 3 | — | 12 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | — | 3 | 2 | 5 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | 1 | 2 | 4 |
| Otitis media | D010033 | EFO_0004992 | H66.9 | — | 1 | 1 | 2 | 1 | 4 |
| Pneumonia | D011014 | EFO_0003106 | — | — | — | — | 2 | 1 | 3 |
| Communicable diseases | D003141 | — | — | — | 1 | — | 1 | 1 | 3 |
| Otitis | D010031 | — | — | — | 1 | 1 | 2 | — | 3 |
| Pituitary neoplasms | D010911 | — | — | — | — | — | 1 | — | 1 |
| Adenoma | D000236 | — | — | — | — | — | 1 | — | 1 |
| Pituitary diseases | D010900 | — | E23.7 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Mastitis | D008413 | EFO_1001034 | N61 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | 2 | — | — | 1 | 3 |
| Cystitis | D003556 | EFO_1000025 | N30 | — | 1 | — | — | — | 1 |
| Anaphylaxis | D000707 | — | T88.6 | — | 1 | — | — | — | 1 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | 1 | — | — | — | 1 |
| Drug hypersensitivity | D004342 | EFO_0009482 | T88.7 | — | 1 | — | — | — | 1 |
| Cephalosporin resistance | D018550 | — | Z16.19 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
| Appendicitis | D001064 | EFO_0007149 | K37 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 1 | 1 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Covid-19 | D000086382 | — | — | — | — | — | — | 1 | 1 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | — | — | — | 1 | 1 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 1 | 1 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 1 | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 1 | 1 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cefdinir |
| INN | cefdinir |
| Description | Cefdinir is a cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups. It has a role as an antibacterial drug. It is a cephalosporin and a ketoxime. |
| Classification | Small molecule |
| Drug class | cephalosporins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\O)c3csc(N)n3)[C@H]2SC1 |
Identifiers
| PDB | — |
| CAS-ID | 91832-40-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL927 |
| ChEBI ID | 3485 |
| PubChem CID | 6915944 |
| DrugBank | DB00535 |
| UNII ID | CI0FAO63WC (ChemIDplus, GSRS) |
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Cefdinir
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Safety
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3,214 adverse events reported
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