Cefaclor
Cefaclor (cefaclor) is a small molecule pharmaceutical. Cefaclor was first approved as Ceclor on 1982-01-01. It is used to treat bacterial infections, bacterial pneumonia, bacterial skin diseases, bronchitis, and escherichia coli infections amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Cefaclor (discontinued: Ceclor, Cefaclor, Raniclor)
Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cefaclor | ANDA | 2024-01-31 |
Indications
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bacterial endocarditis | D004697 | EFO_1000830 | — | — | — | — | 1 | — | 1 |
| Endocarditis | D004696 | HP_0100584 | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic bronchitis | D029481 | — | J42 | — | 1 | 1 | — | — | 1 |
| Bronchitis | D001991 | — | J40 | — | 1 | 1 | — | — | 1 |
| Acute disease | D000208 | — | — | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anaphylaxis | D000707 | — | T88.6 | — | 1 | — | — | — | 1 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | 1 | — | — | — | 1 |
| Drug hypersensitivity | D004342 | EFO_0009482 | T88.7 | — | 1 | — | — | — | 1 |
| Cephalosporin resistance | D018550 | — | Z16.19 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
| Low-level light therapy | D028022 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Snoring | D012913 | — | R06.83 | — | — | — | — | 1 | 1 |
| Acute cholecystitis | D041881 | EFO_1001289 | K81.0 | — | — | — | — | 1 | 1 |
| Cholecystitis | D002764 | HP_0001082 | K81 | — | — | — | — | 1 | 1 |
| Stem cell research | D057905 | — | — | — | — | — | — | 1 | 1 |
| Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 1 | 1 |
| Cholangitis | D002761 | HP_0030151 | K83.0 | — | — | — | — | 1 | 1 |
| Biliary atresia | D001656 | EFO_0004217 | Q44.2 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cefaclor |
| INN | cefaclor |
| Description | Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. It is also available from other manufacturers as a generic.
|
| Classification | Small molecule |
| Drug class | cephalosporins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | N[C@@H](C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(Cl)CS[C@H]12)c1ccccc1.O |
Identifiers
| PDB | — |
| CAS-ID | 53994-73-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201018 |
| ChEBI ID | — |
| PubChem CID | 51038 |
| DrugBank | DB00833 |
| UNII ID | 3Z6FS3IK0K (ChemIDplus, GSRS) |
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Estimated US medical usage
Cefaclor
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Trends
PubMed Central
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Additional graphs summarizing 3,146 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,482 adverse events reported
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