Catequentinib
Catequentinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
463 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 6 | 22 | 8 | 1 | 3 | 35 |
| Lung neoplasms | D008175 | — | C34.90 | 6 | 22 | 8 | 1 | 1 | 31 |
| Small cell lung carcinoma | D055752 | — | — | — | 4 | 3 | 1 | — | 8 |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | — | 3 | 2 | 1 | 1 | 5 |
| Thyroid diseases | D013959 | — | E00-E07 | — | 2 | 2 | 1 | 1 | 4 |
| Papillary thyroid cancer | D000077273 | — | — | — | 1 | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 2 | 11 | 3 | — | — | 14 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 2 | 5 | 2 | — | — | 8 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 4 | 1 | — | — | 6 |
| Colorectal neoplasms | D015179 | — | — | 1 | 3 | 2 | — | — | 5 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | 3 | 1 | — | — | 4 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 4 | 1 | — | — | 4 |
| Sarcoma | D012509 | — | — | — | 3 | 2 | — | — | 4 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | — | 2 | 1 | — | — | 3 |
| Nasopharyngeal neoplasms | D009303 | — | — | 1 | 2 | 1 | — | — | 3 |
| Triple negative breast neoplasms | D064726 | — | — | 1 | — | 1 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 6 | 8 | — | — | — | 13 |
| Recurrence | D012008 | — | — | — | 4 | — | — | — | 4 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | — | 4 | — | — | — | 4 |
| Digestive system neoplasms | D004067 | — | — | — | 4 | — | — | — | 4 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 3 | — | — | — | 3 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | — | 3 | — | — | — | 3 |
| Esophageal neoplasms | D004938 | — | C15 | — | 3 | — | — | — | 3 |
| Gastrointestinal diseases | D005767 | — | — | — | 3 | — | — | — | 3 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | 3 | — | — | — | 3 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | — | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Catequentinib |
| INN | catequentinib |
| Description | Anlotinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 3, fibroblast growth factor receptor 1, and vascular endothelial growth factor receptor 1. |
| Classification | Small molecule |
| Drug class | tyrosine kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1058156-90-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4303201 |
| ChEBI ID | — |
| PubChem CID | 25017411 |
| DrugBank | DB11885 |
| UNII ID | GKF8S4C432 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Safety
Black-box Warning
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Adverse Events
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340 adverse events reported
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