Catequentinib
Catequentinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
508 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 20 | 81 | 13 | 6 | 16 | 118 |
| Lung neoplasms | D008175 | — | C34.90 | 14 | 58 | 13 | 3 | 11 | 86 |
| Small cell lung carcinoma | D055752 | — | — | 3 | 32 | 5 | 3 | 6 | 46 |
| Neoplasms | D009369 | — | C80 | 9 | 20 | 1 | 1 | 1 | 28 |
| Sarcoma | D012509 | — | — | 5 | 19 | 3 | 3 | 2 | 28 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 12 | 1 | 1 | 1 | 16 |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | — | 8 | 2 | 3 | 4 | 15 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 1 | 10 | 1 | 1 | 1 | 14 |
| Thyroid diseases | D013959 | — | E00-E07 | — | 6 | 2 | 3 | 3 | 12 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 4 | — | 1 | 1 | 7 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 4 | 39 | 6 | — | 4 | 47 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 4 | 19 | 4 | — | 4 | 27 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 15 | 3 | — | 4 | 22 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | — | 14 | 1 | — | 1 | 15 |
| Triple negative breast neoplasms | D064726 | — | — | 3 | 11 | 1 | — | 1 | 15 |
| Nasopharyngeal neoplasms | D009303 | — | — | 4 | 11 | 3 | — | — | 15 |
| Colorectal neoplasms | D015179 | — | — | 4 | 10 | 2 | — | — | 13 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | 10 | 1 | — | 3 | 13 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 3 | 9 | 3 | — | — | 13 |
| Squamous cell carcinoma | D002294 | — | — | 1 | 11 | 1 | — | 1 | 12 |
Show 16 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | 21 | — | — | 5 | 28 |
| Recurrence | D012008 | — | — | 4 | 15 | — | — | — | 16 |
| Esophageal neoplasms | D004938 | — | C15 | — | 8 | — | — | 5 | 13 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 4 | 10 | — | — | — | 12 |
| Adenocarcinoma | D000230 | — | — | 3 | 8 | — | — | 1 | 10 |
| Immunotherapy | D007167 | — | — | 1 | 8 | — | — | 1 | 9 |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | 7 | — | — | — | 7 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 1 | 4 | — | — | 2 | 7 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | 1 | 5 | — | — | — | 5 |
| Digestive system neoplasms | D004067 | — | — | 1 | 5 | — | — | — | 5 |
Show 76 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteosarcoma | D012516 | — | — | 2 | — | — | — | — | 2 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | 1 | — | — | — | — | 1 |
| Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chemoradiotherapy | D059248 | — | — | — | — | — | — | 1 | 1 |
| Small cell carcinoma | D018288 | — | — | — | — | — | — | 1 | 1 |
| Desmoid tumors | D018222 | — | D48.11 | — | — | — | — | 1 | 1 |
| Ultrasonography | D014463 | — | — | — | — | — | — | 1 | 1 |
| Colonic neoplasms | D003110 | — | C18 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Catequentinib |
| INN | catequentinib |
| Description | Anlotinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 3, fibroblast growth factor receptor 1, and vascular endothelial growth factor receptor 1. |
| Classification | Small molecule |
| Drug class | tyrosine kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1058156-90-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4303201 |
| ChEBI ID | — |
| PubChem CID | 25017411 |
| DrugBank | DB11885 |
| UNII ID | GKF8S4C432 (ChemIDplus, GSRS) |
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Safety
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Adverse Events
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364 adverse events reported
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