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Drug ReportsCaspofungin
Cancidas, Cancidas (previously caspofungin msd)(caspofungin)
Cancidas, Caspofungin (caspofungin) is a small molecule pharmaceutical. Caspofungin was first approved as Cancidas on 2001-01-26. It is used to treat aspergillosis, candidemia, and mycoses in the USA. It has been approved in Europe to treat aspergillosis and candidiasis.
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Drug
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Financial
Trends
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Caspofungin (discontinued: Cancidas, Caspofungin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Caspofungin acetate
Tradename
Company
Number
Date
Products
CASPOFUNGIN ACETATEFresenius KabiN-206110 RX2016-12-30
2 products
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
cancidasNew Drug Application2024-10-11
caspofungin acetateANDA2025-08-26
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
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FDA Information
Caspofungin Acetate, Caspofungin Acetate, Fresenius Kabi Usa
96364072032-12-21DP
ATC Codes
J: Antiinfectives for systemic use
J02: Antimycotics for systemic use
J02A: Antimycotics for systemic use
J02AX: Other antimycotics for systemic use in atc
J02AX04: Caspofungin
HCPCS
Code
Description
J0637
Injection, caspofungin acetate, 5 mg
Clinical
Clinical Trials
89 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MycosesD009181B35-B4910143835
CandidiasisD002177B37581721
Invasive candidiasisD058365EFO_1001283B37562215
Invasive fungal infectionsD000072742241714
CandidemiaD058387EFO_1001282161412
AspergillosisD001228EFO_0007157B44152411
Invasive pulmonary aspergillosisD055744B44.013216
Critical illnessD016638145
Pneumocystis pneumoniaD011020EFO_0007448B59111125
Liver transplantationD016031EFO_00106821113
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_000054434916
NeutropeniaD009503D701337
FungemiaD016469B49246
LeukemiaD007938C9513216
Myeloid leukemia acuteD015470C92.01235
SepsisD018805EFO_0001420A41.91214
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.01214
FeverD005334R50.91124
NeoplasmsD009369C80213
NeuroblastomaD009447EFO_00006211113
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Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypoalbuminemiaD03414111
Hepatocellular carcinomaD006528C22.011
Respiratory insufficiencyD012131J96.911
FusariosisD060585EFO_100179511
Febrile neutropeniaD06414711
HyperthermiaD00008446211
RecurrenceD01200811
SarcomaD01250911
LymphomaD008223C85.911
Kidney neoplasmsD007680EFO_0003865C6411
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCaspofungin
INNcaspofungin
Description
Caspofungin (INN; brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc.. It is a member of a class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Classification
Small molecule
Drug classantifungal antibiotics (undefined group)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@H]([C@H](O)CCN)NC(=O)[C@H]([C@H](O)[C@@H](O)c2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@@H](C)O)NC1=O
Identifiers
PDB
CAS-ID162808-62-0
RxCUI
ChEMBL IDCHEMBL499808
ChEBI ID474180
PubChem CID16119814
DrugBankDB00520
UNII IDF0XDI6ZL63 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
Cancidas Merck & Co
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Tabular view
Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 13,047 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5,987 adverse events reported
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