Carteolol
Carteolol (carteolol) is a small molecule pharmaceutical. Carteolol was first approved as Cartrol on 1988-12-28. It is used to treat hypertension and open-angle glaucoma in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
| cardiovascular diseases | D002318 |
Trade Name
FDA
EMA
Carteolol (discontinued: Carteolol, Cartrol, Ocupress)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| carteolol hydrochloride | ANDA | 2021-08-31 |
| ocupress | 2006-09-19 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| hypertension | EFO_0000537 | D006973 | I10 |
| open-angle glaucoma | EFO_0004190 | D005902 | H40.1 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C07: Beta-adrenergic blocking agents
— C07A: Beta blocking agents
— C07AA: Beta blocking agents, non-selective
— C07AA15: Carteolol
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01E: Antiglaucoma preparations and miotics
— S01ED: Beta blocking agents, antiglaucoma preparations and miotics
— S01ED05: Carteolol
— S01ED55: Carteolol, combinations
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | 1 | — | 3 | 1 | — | 5 |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | — | 3 | 1 | — | 5 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | 3 | 1 | — | 4 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Carteolol |
| INN | carteolol |
| Description | Carteolol is a quinolone and a secondary alcohol. It has a role as a beta-adrenergic antagonist, an antihypertensive agent, an antiglaucoma drug, an anti-arrhythmia drug and a sympatholytic agent. It is a conjugate base of a carteolol(1+). |
| Classification | Small molecule |
| Drug class | beta-blockers (propranolol type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)NCC(O)COc1cccc2c1CCC(=O)N2 |
Identifiers
| PDB | — |
| CAS-ID | 51781-06-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL839 |
| ChEBI ID | 3437 |
| PubChem CID | 2583 |
| DrugBank | DB00521 |
| UNII ID | 8NF31401XG (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
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Estimated US medical usage
Carteolol
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 817 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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422 adverse events reported
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