Carotuximab
Carotuximab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against endoglin.
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Events Timeline
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Commercial
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Clinical
Clinical Trials
28 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemangiosarcoma | D006394 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 3 | 7 | — | — | — | 7 |
| Neoplasms | D009369 | — | C80 | 3 | 3 | — | — | 1 | 6 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 2 | 3 | — | — | — | 3 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 3 | — | — | — | 3 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | 3 | — | — | — | 3 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 3 | — | — | — | 3 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | 2 | — | — | — | 2 |
| Choriocarcinoma | D002822 | — | C58 | — | 2 | — | — | — | 2 |
| Recurrence | D012008 | — | — | 1 | 2 | — | — | — | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 3 | — | — | — | — | 3 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 3 | — | — | — | — | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Carotuximab |
| INN | carotuximab |
| Description | TRC-105 (chimeric mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109321 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | YB2EWE6139 (ChemIDplus, GSRS) |
Target
Variants
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Financial
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Trends
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Additional graphs summarizing 601 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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16 adverse events reported
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