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Drug ReportsCarotuximab
Carotuximab
Carotuximab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against endoglin.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
28 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Macular degenerationD008268EFO_0001365H35.3012———2
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCarotuximab
INNcarotuximab
Description
TRC-105 (chimeric mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2109321
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDYB2EWE6139 (ChemIDplus, GSRS)
Target
Agency Approved
ENG
ENG
Organism
Homo sapiens
Gene name
ENG
Gene synonyms
END
NCBI Gene ID
Protein name
endoglin
Protein synonyms
CD105, CD105 antigen, soluble endoglin
Uniprot ID
Mouse ortholog
Eng (13805)
endoglin (Q8K100)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 617 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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16 adverse events reported
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