Therapeutic Area | MeSH |
---|---|
mental disorders | D001523 |
Brand Name | Status | Last Update |
---|---|---|
vraylar | New Drug Application | 2024-11-22 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
schizophrenia | EFO_0000692 | D012559 | F20 |
bipolar disorder | EFO_0000289 | D001714 | F30.9 |
schizophrenia spectrum and other psychotic disorders | — | D019967 | — |
Expiration | Code | ||
---|---|---|---|
CARIPRAZINE HYDROCHLORIDE, VRAYLAR, ABBVIE | |||
2025-12-16 | I-904 |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Cariprazine Hydrochloride, Vraylar, Abbvie | |||
7737142 | 2029-09-17 | DS, DP | U-1750, U-2543, U-2544, U-2545, U-3503 |
RE47350 | 2029-07-16 | U-1750, U-2543, U-2544, U-2545, U-3503 | |
RE49110 | 2029-07-16 | U-2543, U-2544, U-2545, U-3503 | |
RE49302 | 2029-07-16 | U-2543, U-2544, U-2545, U-3503 | |
7943621 | 2028-12-16 | DS, DP |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | 1 | — | 1 | — | 2 |
Social phobia | D000072861 | EFO_1001917 | F40.1 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Depression | D003863 | — | F33.9 | — | — | 4 | — | — | 4 |
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | 3 | — | 1 | 4 |
Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | 3 | — | — | 3 |
Autistic disorder | D001321 | HP_0000717 | F84.0 | 1 | — | 2 | — | — | 3 |
Autism spectrum disorder | D000067877 | HP_0000729 | F84.0 | 1 | — | 2 | — | — | 3 |
Pervasive child development disorders | D002659 | EFO_0003756 | F84 | — | — | 2 | — | — | 2 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | 2 | — | — | 2 |
Depressive disorder | D003866 | EFO_1002014 | F32.A | — | — | 2 | — | — | 2 |
Recurrence | D012008 | — | — | — | — | 1 | — | — | 1 |
Mania | D000087122 | — | — | — | — | 1 | — | — | 1 |
Drug common name | Cariprazine |
INN | cariprazine |
Description | Cariprazine is an N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder. It has a role as a dopamine agonist, a second generation antipsychotic and a serotonergic antagonist. It is a member of ureas, a N-alkylpiperazine, a N-arylpiperazine and a dichlorobenzene. It is a conjugate base of a cariprazine(1+). |
Classification | Small molecule |
Drug class | Atypical antipsychotic |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1 |
PDB | — |
CAS-ID | 839712-12-8 |
RxCUI | — |
ChEMBL ID | CHEMBL2028019 |
ChEBI ID | — |
PubChem CID | 11154555 |
DrugBank | DB06016 |
UNII ID | F6RJL8B278 (ChemIDplus, GSRS) |