Carboplatin
Carboplatin (carboplatin) is a small molecule pharmaceutical. Carboplatin was first approved as Paraplatin on 1989-03-03. It is used to treat bone marrow diseases, breast neoplasms, central nervous system neoplasms, endometrial neoplasms, and esophageal neoplasms amongst others in the USA.
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Commercial
Trade Name
FDA
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Carboplatin (discontinued: Carboplatin, Paraplatin)
Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Carboplatin
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PARAPLATIN | CordenPharma | N-019880 DISCN | 1989-03-03 | 3 products, RLD |
| PARAPLATIN | CordenPharma | N-020452 DISCN | 2003-07-14 | 4 products, RLD |
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| carboplatin | ANDA | 2025-05-23 |
| kyxata | New Drug Application | 2025-09-02 |
Indications
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Agency Specific
FDA
EMA
No data
Patent Expiration
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HCPCS
Code | Description |
|---|---|
| J9045 | Injection, carboplatin, 50 mg |
Clinical
Clinical Trials
4012 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 2 | — | — | 2 |
| Mucinous adenocarcinoma | D002288 | — | — | — | 1 | 2 | — | — | 2 |
| Ductal carcinoma breast | D018270 | — | — | — | 1 | 2 | — | — | 2 |
| Inflammatory breast neoplasms | D058922 | — | — | — | 1 | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | — | C61 | — | 1 | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | — | 1 | — | — | — | 1 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | 1 | — | — | — | 1 |
| Myeloid leukemia acute | D015470 | — | C92.0 | — | 1 | — | — | — | 1 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | — | 1 | — | — | — | 1 |
| Myeloid leukemia | D007951 | — | C92 | — | 1 | — | — | — | 1 |
| Myelomonocytic leukemia juvenile | D054429 | — | C93.3 | — | 1 | — | — | — | 1 |
| Preleukemia | D011289 | — | — | — | 1 | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Carboplatin |
| INN | carboplatin |
| Description | Carboplatin, sold under the trade name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer. This includes ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma. It is used by injection into a vein.
|
| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 41575-94-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1351 |
| ChEBI ID | 31355 |
| PubChem CID | 10339178 |
| DrugBank | DB00958 |
| UNII ID | BG3F62OND5 (ChemIDplus, GSRS) |
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Additional graphs summarizing 87,731 documents
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Safety
Black-box Warning
Black-box warning for: Carboplatin, Kyxata
Adverse Events
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106,311 adverse events reported
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