Capreomycin
Capastat (capreomycin) is a protein pharmaceutical. Capreomycin was first approved as Capastat sulfate on 1982-01-01. It is used to treat mycobacterium infections and tuberculosis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Capreomycin sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CAPASTAT SULFATE | Epic Pharma | N-050095 DISCN | 1982-01-01 | 1 products, RLD |
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Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| tuberculosis | EFO_0000774 | D014376 | A15-A19 |
| mycobacterium infections | — | D009164 | A31.9 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
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Drug
General
| Drug common name | Capreomycin |
| INN | capreomycin |
| Description | Capreomycin is an antibiotic which is given in combination with other antibiotics for the treatment of tuberculosis. Specifically it is a second line treatment used for active drug resistant tuberculosis. It is given by injection into a vein or muscle.
|
| Classification | Protein |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1NC(=O)[C@@H](N)CNC(=O)[C@H](C2CCNC(=N)N2)NC(=O)/C(=C/NC(N)=O)NC(=O)[C@H](CNC(=O)CC(N)CCCN)NC1=O.N=C1NCCC([C@@H]2NC(=O)/C(=C/NC(N)=O)NC(=O)[C@H](CNC(=O)CC(N)CCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CNC2=O)N1 |
Identifiers
| PDB | — |
| CAS-ID | 11003-38-6 |
| RxCUI | 78903 |
| ChEMBL ID | CHEMBL2221250 |
| ChEBI ID | — |
| PubChem CID | 135483770 |
| DrugBank | DB00314 |
| UNII ID | 232HYX66HC (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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