Camrelizumab
Camrelizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target programmed cell death protein 1.
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Commercial
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Clinical
Clinical Trials
605 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 1 | 22 | 7 | — | — | 28 |
| Non-small-cell lung carcinoma | D002289 | — | — | 2 | 9 | 6 | — | 1 | 16 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 10 | 6 | — | — | 15 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 6 | 4 | — | 1 | 11 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 6 | 4 | — | — | 10 |
| Squamous cell carcinoma | D002294 | — | — | — | 9 | 1 | — | — | 10 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | — | 7 | 2 | — | — | 9 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 7 | 3 | — | — | 9 |
| Esophageal neoplasms | D004938 | — | C15 | — | 3 | 3 | — | 2 | 8 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 4 | 2 | — | — | 6 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 7 | 6 | — | — | — | 12 |
| Osteosarcoma | D012516 | — | — | 1 | 3 | — | — | 1 | 4 |
| Adenocarcinoma | D000230 | — | — | — | 3 | — | — | — | 3 |
| Sarcoma | D012509 | — | — | — | 3 | — | — | — | 3 |
| Small cell lung carcinoma | D055752 | — | — | — | 2 | — | — | 1 | 3 |
| Colorectal neoplasms | D015179 | — | — | — | 2 | — | — | — | 2 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | 1 | 2 |
| Glioblastoma | D005909 | EFO_0000515 | — | — | 2 | — | — | — | 2 |
| Cholangiocarcinoma | D018281 | — | C22.1 | — | 2 | — | — | — | 2 |
| Biliary tract neoplasms | D001661 | — | C24.9 | — | 2 | — | — | — | 2 |
Show 17 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | — | C92.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Camrelizumab |
| INN | camrelizumab |
| Description | Camrelizumab (SHR-1210) (INN) is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | 7CU5 |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297715 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 73096E137E (ChemIDplus, GSRS) |
Target
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PDCD1
PDCD1
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Safety
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412 adverse events reported
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