Camrelizumab
Camrelizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target programmed cell death protein 1.
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Commercial
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Clinical
Clinical Trials
556 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 18 | 104 | 27 | 1 | 28 | 161 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 10 | 44 | 13 | 1 | 28 | 86 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 6 | 27 | 8 | 1 | 8 | 47 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 6 | 38 | 9 | — | 24 | 69 |
| Squamous cell carcinoma | D002294 | — | — | 7 | 42 | 4 | — | 3 | 51 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 6 | 36 | 4 | — | 6 | 47 |
| Non-small-cell lung carcinoma | D002289 | — | — | 4 | 30 | 9 | — | 6 | 46 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 7 | 31 | 9 | — | 1 | 43 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | 7 | 28 | 3 | — | 3 | 36 |
| Neoplasms | D009369 | — | C80 | 11 | 21 | 4 | — | 2 | 33 |
| Esophageal neoplasms | D004938 | — | C15 | 3 | 21 | 7 | — | 5 | 33 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 1 | 18 | 12 | — | — | 30 |
| Triple negative breast neoplasms | D064726 | — | — | 5 | 20 | 8 | — | 1 | 29 |
Show 29 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 6 | 15 | — | — | 4 | 20 |
| Biliary tract neoplasms | D001661 | — | C24.9 | 2 | 10 | — | — | — | 10 |
| Cholangiocarcinoma | D018281 | — | C22.1 | — | 8 | — | — | 2 | 10 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 9 | — | — | 1 | 10 |
| Sarcoma | D012509 | — | — | 1 | 9 | — | — | — | 10 |
| Osteosarcoma | D012516 | — | — | 1 | 4 | — | — | 2 | 6 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | 2 | 4 | — | — | — | 6 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | — | 4 | — | — | 2 | 6 |
| T-cell lymphoma | D016399 | — | — | 2 | 4 | — | — | 1 | 5 |
| T-cell lymphoma peripheral | D016411 | — | — | 2 | 4 | — | — | 1 | 5 |
Show 66 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Mouth neoplasms | D009062 | EFO_0003868 | C06.9 | 1 | — | — | — | — | 1 |
| Hematologic neoplasms | D019337 | — | — | 1 | — | — | — | — | 1 |
| Hyperbaric oxygenation | D006931 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver diseases | D008107 | HP_0002910 | K70-K77 | — | — | — | — | 2 | 2 |
| Thrombosis | D013927 | — | — | — | — | — | — | 2 | 2 |
| Catheter ablation | D017115 | — | — | — | — | — | — | 2 | 2 |
| Stents | D015607 | — | — | — | — | — | — | 1 | 1 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | — | — | — | 1 | 1 |
| Clear cell adenocarcinoma | D018262 | — | — | — | — | — | — | 1 | 1 |
| Adenomyoepithelioma | D055331 | — | — | — | — | — | — | 1 | 1 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | — | — | — | — | 1 | 1 |
| Male breast neoplasms | D018567 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Camrelizumab |
| INN | camrelizumab |
| Description | Camrelizumab (SHR-1210) (INN) is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | 7CU5 |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297715 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 73096E137E (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
PDCD1
PDCD1
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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259 adverse events reported
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